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Properties of Samples With Segregating Polymerase Chain Reaction (PCR) Dropout Mutations Within a Species
In polymerase chain reaction (PCR)-based DNA sequencing studies, there is the possibility that mutations at the binding sites of primers result in no primer binding and therefore no amplification. In this article, we call such mutations PCR dropouts and present a coalescent-based theory of the distr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831972/ https://www.ncbi.nlm.nih.gov/pubmed/31723319 http://dx.doi.org/10.1177/1176934319883612 |