Comparative analysis between four model nanoformulations of amphotericin B-chitosan, amphotericin B-dendrimer, betulinic acid-chitosan and betulinic acid-dendrimer for treatment of Leishmania major: real-time PCR assay plus

BACKGROUND: Amphotericin B (Amp) and Betulinic acid (BA) as antileishmanial agents have negligible water solubility and high toxicity. To solve these problems, for the first time, chitosan nanoparticles and Anionic Linear Globular Dendrimer (D) were synthesized for the treatment of Leishmania major...

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Detalles Bibliográficos
Autores principales: Zadeh Mehrizi, Tahereh, Khamesipour, Ali, Shafiee Ardestani, Mehdi, Ebrahimi Shahmabadi, Hasan, Haji Molla Hoseini, Mostafa, Mosaffa, Nariman, Ramezani, Amitis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831986/
https://www.ncbi.nlm.nih.gov/pubmed/31802863
http://dx.doi.org/10.2147/IJN.S220410

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