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Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells
Clostridium perfringens enterotoxin (CPE) contributes to diarrhea and an often-lethal enterotoxemia. CPE action starts when it binds to claudin receptors, forming a small complex (90 kDa). Six small complexes then oligomerize to create prepores, followed by insertion of beta-hairpins from CPE to for...
Autores principales: | Mehdizadeh Gohari, Iman, Li, Jihong, Navarro, Mauricio, Uzal, Francisco, McClane, Bruce |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832201/ https://www.ncbi.nlm.nih.gov/pubmed/31601044 http://dx.doi.org/10.3390/toxins11100582 |
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