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Vaso-Occlusion in Sickle Cell Disease: Is Autonomic Dysregulation of the Microvasculature the Trigger?
Sickle cell disease (SCD) is an inherited hemoglobinopathy characterized by polymerization of hemoglobin S upon deoxygenation that results in the formation of rigid sickled-shaped red blood cells that can occlude the microvasculature, which leads to sudden onsets of pain. The severity of vaso-occlus...
Autores principales: | Veluswamy, Saranya, Shah, Payal, Denton, Christopher C., Chalacheva, Patjanaporn, Khoo, Michael C. K., Coates, Thomas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832215/ https://www.ncbi.nlm.nih.gov/pubmed/31618931 http://dx.doi.org/10.3390/jcm8101690 |
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