Natural Sesquiterpene Lactones of the 4,15-iso-Atriplicolide Type are Inhibitors of Trypanothione Reductase

In the course of our investigations on the antitrypanosomal potential of sesquiterpene lactones (STL), we have recently reported on the exceptionally strong activity of 4,15-iso-Atriplicolide tiglate, which demonstrated an IC(50) value of 15 nM against Trypanosoma brucei rhodesiense, the etiologic a...

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Detalles Bibliográficos
Autores principales: Lenz, Mairin, Krauth-Siegel, R. Luise, Schmidt, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832266/
https://www.ncbi.nlm.nih.gov/pubmed/31623252
http://dx.doi.org/10.3390/molecules24203737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832266/
https://www.ncbi.nlm.nih.gov/pubmed/31623252
http://dx.doi.org/10.3390/molecules24203737

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