Cargando…

Penfluridol as a Candidate of Drug Repurposing for Anticancer Agent

Penfluridol has robust antipsychotic efficacy and is a first-generation diphenylbutylpiperidine. Its effects last for several days after a single oral dose and it can be administered once a week to provide better compliance and symptom control. Recently; strong antitumour effects for penfluridol wer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tuan, Nguyen Minh, Lee, Chang Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832311/ https://www.ncbi.nlm.nih.gov/pubmed/31614431 http://dx.doi.org/10.3390/molecules24203659

Ejemplares similares

Ethacrynic Acid: A Promising Candidate for Drug Repurposing as an Anticancer Agent
por: Yu, Lu, et al.
Publicado: (2023)

Repurposing Penfluridol in Combination with Temozolomide for the Treatment of Glioblastoma
por: Kim, Hyungsin, et al.
Publicado: (2019)

Drug repurposing: Antimicrobial and antibiofilm effects of penfluridol against Enterococcus faecalis
por: Zeng, Xianghai, et al.
Publicado: (2020)

Synergistic Tumor Inhibition via Energy Elimination by Repurposing Penfluridol and 2-Deoxy-D-Glucose in Lung Cancer
por: Lai, Tsung-Ching, et al.
Publicado: (2022)

Drug repurposing against COVID-19: focus on anticancer agents
por: Ciliberto, Gennaro, et al.
Publicado: (2020)

PENFLURIDOL MAINTENANCE THERAPY IN SCHIZOPHRENIA: A CONTROLLED STUDY
por: Channabasavanna, S.M., et al.
Publicado: (1987)

Penfluridol overcomes paclitaxel resistance in metastatic breast cancer
por: Gupta, Nehal, et al.
Publicado: (2019)

Low Dose of Penfluridol Inhibits VEGF-Induced Angiogenesis
por: Srivastava, Suyash, et al.
Publicado: (2020)

Repurposing Tranexamic Acid as an Anticancer Agent
por: Law, Mary E., et al.
Publicado: (2022)

Repurposing anticancer drugs for the management of COVID-19
por: El Bairi, Khalid, et al.
Publicado: (2020)

COVID-19 Molecular Pathophysiology: Acetylation of Repurposing Drugs
por: Lee, Jong Hoon, et al.
Publicado: (2022)

Penfluridol suppresses pancreatic tumor growth by autophagy-mediated apoptosis
por: Ranjan, Alok, et al.
Publicado: (2016)

Repurposable Drugs for Immunotherapy and Strategies to Find Candidate Drugs
por: Sakai, Norihiro, et al.
Publicado: (2023)

Anticancer drugs repurposed for Alzheimer’s disease: a systematic review
por: Ancidoni, Antonio, et al.
Publicado: (2021)

Immune consequences of penfluridol treatment associated with inhibition of glioblastoma tumor growth
por: Ranjan, Alok, et al.
Publicado: (2017)

Antimicrobial, Antibiofilm, and Anti-persister Activities of Penfluridol Against Staphylococcus aureus
por: Liu, Yaqian, et al.
Publicado: (2021)

Drug Repurposing of Metabolic Agents in Malignant Glioma
por: Seliger, Corinna, et al.
Publicado: (2018)

Penfluridol suppresses glioblastoma tumor growth by Akt-mediated inhibition of GLI1
por: Ranjan, Alok, et al.
Publicado: (2017)

Enhancing the anticancer immune response with the assistance of drug repurposing and delivery systems
por: Fu, Zile, et al.
Publicado: (2023)

The wisdom of crowds and the repurposing of artesunate as an anticancer drug
por: Augustin, Yolanda, et al.
Publicado: (2015)

Fruit fly for anticancer drug discovery and repurposing
por: Nainu, Firzan, et al.
Publicado: (2023)

Towards Drug Repurposing in Cancer Cachexia: Potential Targets and Candidates
por: Santos, Joana M. O., et al.
Publicado: (2021)

Repurposing the anticancer drug cisplatin with the aim of developing novel Pseudomonas aeruginosa infection control agents
por: Yuan, Mingjun, et al.
Publicado: (2018)

Repurposing Cannabidiol as a Potential Drug Candidate for Anti-Tumor Therapies
por: Wang, Fei, et al.
Publicado: (2021)

Anticancer Properties of Fenofibrate: A Repurposing Use
por: Lian, Xin, et al.
Publicado: (2018)

Artemisinin and Its Derivatives as a Repurposing Anticancer Agent: What Else Do We Need to Do?
por: Li, Zhe, et al.
Publicado: (2016)

Repurposing of Drug Candidates for Treatment of Skin Cancer
por: Cortés, Hernán, et al.
Publicado: (2021)

Drug repurposing strategies in the development of potential antifungal agents
por: Zhang, Qian, et al.
Publicado: (2021)

Mebendazole as a Candidate for Drug Repurposing in Oncology: An Extensive Review of Current Literature
por: Guerini, Andrea Emanuele, et al.
Publicado: (2019)

Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases
por: Chen, Yue-hong, et al.
Publicado: (2022)

Inhibition of AMPK/PFKFB3 mediated glycolysis synergizes with penfluridol to suppress gallbladder cancer growth
por: Hu, Jiahao, et al.
Publicado: (2022)

Repurposing old drugs as antiviral agents for coronaviruses
por: Yang, Cheng-Wei, et al.
Publicado: (2020)

Repurposing Old Drugs into New Epigenetic Inhibitors: Promising Candidates for Cancer Treatment?
por: Moreira-Silva, Filipa, et al.
Publicado: (2020)

Benefits and adverse effects of hydroxychloroquine, methotrexate and colchicine: searching for repurposable drug candidates
por: Misra, Durga Prasanna, et al.
Publicado: (2020)

Anti-Inflammatory Drugs as Anticancer Agents
por: Zappavigna, Silvia, et al.
Publicado: (2020)

Preclinical pharmacodynamic evaluation of antibiotic nitroxoline for anticancer drug repurposing
por: ZHANG, QI, et al.
Publicado: (2016)

Effects of repurposed drug candidates nitroxoline and nelfinavir as single agents or in combination with erlotinib in pancreatic cancer cells
por: Veschi, Serena, et al.
Publicado: (2018)

Recent Advances in Repurposing Disulfiram and Disulfiram Derivatives as Copper-Dependent Anticancer Agents
por: Kannappan, Vinodh, et al.
Publicado: (2021)

Targeting DRD2 by the antipsychotic drug, penfluridol, retards growth of renal cell carcinoma via inducing stemness inhibition and autophagy-mediated apoptosis
por: Tung, Min-Che, et al.
Publicado: (2022)

Systematically Prioritizing Candidates in Genome-Based Drug Repurposing
por: Challa, Anup P., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_t1bom21rdvp2p055t3oeo8l5n3