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A New Cell Model for Investigating Prion Strain Selection and Adaptation

Prion diseases are fatal neurodegenerative diseases that affect humans and animals. Prion strains, conformational variants of misfolded prion proteins, are associated with distinct clinical and pathological phenotypes. Host-strain interactions result in the selective damage of distinct brain areas a...

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Detalles Bibliográficos
Autores principales:	Philiastides, Alexandra, Ribes, Juan Manuel, Yip, Daniel Chun-Mun, Schmidt, Christian, Benilova, Iryna, Klöhn, Peter-Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832381/ https://www.ncbi.nlm.nih.gov/pubmed/31546723 http://dx.doi.org/10.3390/v11100888

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