Cargando…

G-Quadruplex-Forming Aptamers—Characteristics, Applications, and Perspectives

G-quadruplexes constitute a unique class of nucleic acid structures formed by G-rich oligonucleotides of DNA- or RNA-type. Depending on their chemical nature, loops length, and localization in the sequence or structure molecularity, G-quadruplexes are highly polymorphic structures showing various fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roxo, Carolina, Kotkowiak, Weronika, Pasternak, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832456/ https://www.ncbi.nlm.nih.gov/pubmed/31640176 http://dx.doi.org/10.3390/molecules24203781

Ejemplares similares

Beyond G-Quadruplexes—The Effect of Junction with Additional Structural Motifs on Aptamers Properties
por: Kotkowiak, Weronika, et al.
Publicado: (2021)

G4 Matters—The Influence of G-Quadruplex Structural Elements on the Antiproliferative Properties of G-Rich Oligonucleotides
por: Roxo, Carolina, et al.
Publicado: (2021)

A Comprehensive Analysis of the Thrombin Binding Aptamer Containing Functionalized Pyrrolo-2’-deoxycytidines
por: Kotkowiak, Weronika, et al.
Publicado: (2021)

Novel isoguanine derivative of unlocked nucleic acid—Investigations of thermodynamics and biological potential of modified thrombin binding aptamer
por: Kotkowiak, Weronika, et al.
Publicado: (2018)

Changes in physicochemical and anticancer properties modulated by chemically modified sugar moieties within sequence-related G-quadruplex structures
por: Roxo, Carolina, et al.
Publicado: (2022)

Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative
por: Kotkowiak, Weronika, et al.
Publicado: (2017)

G-Quadruplex-Based Fluorescent Turn-On Ligands and Aptamers: From Development to Applications
por: Umar, Mubarak I., et al.
Publicado: (2019)

G-Quadruplex Aptamer-Ligand Characterization
por: Moreira, David, et al.
Publicado: (2022)

G-quadruplex-forming aptamer enhances the peroxidase activity of myoglobin against luminol
por: Tsukakoshi, Kaori, et al.
Publicado: (2021)

Thermodynamic Features of Structural Motifs Formed by β-L-RNA
por: Szabat, Marta, et al.
Publicado: (2016)

Truncated Analogues of a G-Quadruplex-Forming Aptamer Targeting Mutant Huntingtin: Shorter Is Better!
por: Riccardi, Claudia, et al.
Publicado: (2022)

Theranostic Application of a Novel G-Quadruplex-Forming DNA Aptamer Targeting Malate Synthase of Mycobacterium tuberculosis
por: Dhiman, Abhijeet, et al.
Publicado: (2019)

Studies on Transcriptional Incorporation of 5’-N-Triphosphates of 5’-Amino-5’-Deoxyribonucleosides
por: Kotkowiak, Weronika, et al.
Publicado: (2016)

The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell
por: Perrone, Rosalba, et al.
Publicado: (2016)

Studying DNA G-Quadruplex Aptamer by (19)F NMR
por: Ishizuka, Takumi, et al.
Publicado: (2017)

Engineering G-quadruplex aptamer to modulate its binding specificity
por: Li, Long, et al.
Publicado: (2020)

Charge-Transfer Interactions Stabilize G-Quadruplex-Forming Thrombin Binding Aptamers and Can Improve Their Anticoagulant Activity
por: Pérez de Carvasal, Kévan, et al.
Publicado: (2021)

G-Quadruplex Forming Oligonucleotides as Anti-HIV Agents
por: Musumeci, Domenica, et al.
Publicado: (2015)

Hybridization Properties of RNA Containing 8-Methoxyguanosine and 8-Benzyloxyguanosine
por: Baranowski, Daniel Sylwester, et al.
Publicado: (2015)

An intermolecular G-quadruplex as the basis for GTP recognition in the class V–GTP aptamer
por: Nasiri, Amir H., et al.
Publicado: (2016)

Structural and Affinity Analyses of G-Quadruplex DNA Aptamers for Camptothecin Derivatives
por: Fujita, Hiroto, et al.
Publicado: (2013)

G-quadruplex-based aptamers against protein targets in therapy and diagnostics()
por: Platella, Chiara, et al.
Publicado: (2017)

Thrombin binding aptamer G-quadruplex stabilized by pyrene-modified nucleotides
por: Kovačič, Matic, et al.
Publicado: (2020)

Detection of CpG Methylation in G-Quadruplex Forming Sequences Using G-Quadruplex Ligands
por: Hasegawa, Hijiri, et al.
Publicado: (2021)

Improved in Vitro Efficacy of Gold Nanoconstructs by Increased Loading of G-quadruplex Aptamer
por: Dam, Duncan Hieu M., et al.
Publicado: (2014)

Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer
por: Opazo, Felipe, et al.
Publicado: (2015)

Gemcitabine-Incorporated G-Quadruplex Aptamer for Targeted Drug Delivery into Pancreas Cancer
por: Park, Jun Young, et al.
Publicado: (2018)

Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif
por: Schofield, Peter, et al.
Publicado: (2023)

Selective targeting of parallel G-quadruplex structure using L-RNA aptamer
por: Ji, Danyang, et al.
Publicado: (2023)

G-Quadruplex-Forming DNA Aptamers Inhibit the DNA-Binding Function of HupB and Mycobacterium tuberculosis Entry into Host Cells
por: Kalra, Priya, et al.
Publicado: (2018)

Fighting the Huntington’s Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies
por: Riccardi, Claudia, et al.
Publicado: (2022)

Perspectives for Applying G-Quadruplex Structures in Neurobiology and Neuropharmacology
por: Asamitsu, Sefan, et al.
Publicado: (2019)

Modulation of Aptamer–Ligand-Binding by Complementary Oligonucleotides: A G-Quadruplex Anti-Ochratoxin A Aptamer Case Study
por: Samokhvalov, Alexey V., et al.
Publicado: (2022)

Putative HIV and SIV G-Quadruplex Sequences in Coding and Noncoding Regions Can Form G-Quadruplexes
por: Krafčíková, Petra, et al.
Publicado: (2017)

Stability of the Na(+) Form of the Human Telomeric G-Quadruplex: Role of Adenines in Stabilizing G-Quadruplex Structure
por: Tucker, Brenna A., et al.
Publicado: (2018)

Aptamer-based Targeted Delivery of a G-quadruplex Ligand in Cervical Cancer Cells
por: Carvalho, Josué, et al.
Publicado: (2019)

Single-molecule detection of folding and unfolding of the G-quadruplex aptamer in a nanopore nanocavity
por: Shim, Ji Wook, et al.
Publicado: (2009)

A Grafting Strategy for the Design of Improved G-Quadruplex Aptamers and High-Activity DNAzymes
por: Li, Tao, et al.
Publicado: (2009)

In silico direct folding of thrombin-binding aptamer G-quadruplex at all-atom level
por: Yang, Changwon, et al.
Publicado: (2017)

Probing the Importance of the G-Quadruplex Grooves for the Activity of the Anti-HIV-Integrase Aptamer T30923
por: Esposito, Veronica, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_glljok6h5t3guaoueh1ktq4ehv