Cargando…

Sequential Annulations to Interesting Novel Pyrrolo[3,2-c]carbazoles

Herein we report a significant, valuable extension of a recently implemented pyrrole benzannulation methodology that, employing versatile nitrodienes from our lab as useful C(4) building blocks, led to indole derivatives characterized by unusual patterns of substitution. The 6-nitro-7-arylindoles re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Benzi, Alice, Bianchi, Lara, Maccagno, Massimo, Pagano, Angela, Petrillo, Giovanni, Tavani, Cinzia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832463/ https://www.ncbi.nlm.nih.gov/pubmed/31652581 http://dx.doi.org/10.3390/molecules24203802

Ejemplares similares

Reactivity of ethyl nitrosoacrylate toward pyrrole, indole and pyrrolo[3,2-c]carbazole: an experimental and theoretical study
por: Benzi, Alice, et al.
Publicado: (2023)

An Easy Access to Furan-Fused Polyheterocyclic Systems
por: Benzi, Alice, et al.
Publicado: (2022)

Efficient synthesis of polyfunctionalized carbazoles and pyrrolo[3,4-c]carbazoles via domino Diels–Alder reaction
por: Fang, Ren-Jie, et al.
Publicado: (2021)

Densely Functionalized 2-Methylideneazetidines: Evaluation as Antibacterials
por: Petrillo, Giovanni, et al.
Publicado: (2021)

3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From Calcium-Channel Modulators Properties to Multidrug-Resistance Reverting Activity
por: Micucci, Matteo, et al.
Publicado: (2020)

Synthesis, Anticonvulsant, Sedative and Anxiolytic Activities of Novel Annulated Pyrrolo[1,4]benzodiazepines
por: Sorra, Kumaraswamy, et al.
Publicado: (2014)

A Versatile Pd-Catalyzed Alkyne Annulation Process for Benzo[a]carbazoles and their Anticancer Analogues
por: Sarmah, Manashi, et al.
Publicado: (2022)

Direct synthesis of aryl-annulated [c]carbazoles by gold(i)-catalysed cascade reaction of azide-diynes and arenes
por: Kawada, Yuiki, et al.
Publicado: (2018)

Annellation of Triazole and Tetrazole Systems onto Pyrrolo[2,3-d]pyrimidines: Synthesis of Tetrazolo[1,5-c]-pyrrolo[3,2-e]-pyrimidines and Triazolo[1,5-c]pyrrolo-[3,2-e]pyrimidines as Potential Antibacterial Agents
por: Dave, Chaitanya G., et al.
Publicado: (2002)

Simple synthesis of pyrrolo[3,2-e]indole-1-carbonitriles
por: Trawczyński, Adam, et al.
Publicado: (2013)

Contributing to Biochemistry and Optoelectronics: Pyrrolo[1′,2′:2,3]imidazo[1,5-a]indoles and Cyclohepta[4,5]pyrrolo[1,2-c]pyrrolo[1,2-a]imidazoles via [3+2] Annulation of Acylethynylcycloalka[b]pyrroles with Δ(1)-Pyrrolines
por: Oparina, Ludmila A., et al.
Publicado: (2023)

Synthesis of pyrrolo[3,2-a]phenazines from 5-nitroindoles and anilines
por: Wróbel, Zbigniew, et al.
Publicado: (2013)

Understanding the mechanism of action of pyrrolo[3,2-b]quinoxaline-derivatives as kinase inhibitors
por: Unzue, Andrea, et al.
Publicado: (2020)

Going beyond the borders: pyrrolo[3,2-b]pyrroles with deep red emission
por: Tasior, Mariusz, et al.
Publicado: (2021)

Targeting of the Mitochondrial TET1 Protein by Pyrrolo[3,2-b]pyrrole Chelators
por: Antonyová, Veronika, et al.
Publicado: (2022)

Diversity oriented one-pot three-component sequential synthesis of annulated benzothiazoloquinazolines
por: Kumar, Mahendra, et al.
Publicado: (2012)

Design, synthesis and molecular docking of new fused 1H-pyrroles, pyrrolo[3,2-d]pyrimidines and pyrrolo[3,2-e][1, 4]diazepine derivatives as potent EGFR/CDK2 inhibitors
por: Belal, Amany, et al.
Publicado: (2022)

Deciphering the unusual fluorescence in weakly coupled bis-nitro-pyrrolo[3,2-b]pyrroles
por: Poronik, Yevgen M., et al.
Publicado: (2020)

Synthesis of Aromatic Aza-metallapentalenes from Metallabenzene via Sequential Ring Contraction/Annulation
por: Wang, Tongdao, et al.
Publicado: (2015)

Combining silver- and organocatalysis: an enantioselective sequential catalytic approach towards pyrano-annulated pyrazoles
por: Hack, Daniel, et al.
Publicado: (2015)

Pyrrolo[3,2-c]pyridine derivatives with potential inhibitory effect against FMS kinase: in vitro biological studies
por: El-Gamal, Mohammed I., et al.
Publicado: (2018)

Method for the Large-Scale Synthesis of Multifunctional 1,4-Dihydro-pyrrolo[3,2-b]pyrroles
por: Tasior, Mariusz, et al.
Publicado: (2020)

5,11-Dimethyl-6,12-dimethoxyindolo[3,2-b]carbazole
por: Wrobel, Norma, et al.
Publicado: (2013)

Indolo[3,2-a]carbazoles from a Deep-Water Sponge of the Genus Asteropus
por: Russell, Floyd, et al.
Publicado: (2013)

2-(4-Methoxyphenyl)-6-trifluoromethyl-1H-pyrrolo[3,2-c]quinoline monohydrate
por: Dutkiewicz, Grzegorz, et al.
Publicado: (2010)

Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization
por: Yang, Chao, et al.
Publicado: (2016)

Nitration of 5,11-dihydroindolo[3,2-b]carbazoles and synthetic applications of their nitro-substituted derivatives
por: Irgashev, Roman A, et al.
Publicado: (2017)

5′,11′-Dihydrodispiro[cyclohexane-1,6′-indolo[3,2-b]carbazole-12′,1′′-cyclohexane]
por: Guzei, Ilia A., et al.
Publicado: (2011)

α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo[1,2-a]quinoxalines, quinazolinones, and other N-heterocycles via decarboxylative oxidative annulation reaction
por: Viji, Mayavan, et al.
Publicado: (2020)

6,12-Bis(hexyloxy)-5H,11H-indolo[3,2-b]carbazole
por: Wrobel, Norma, et al.
Publicado: (2012)

Novel Indolocarbazole Derivative 12-(α-L-arabinopyranosyl)indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione Is a Preferred c-Myc Guanine Quadruplex Ligand
por: Kaluzhny, Dmitry N., et al.
Publicado: (2011)

Recent Strategies in Transition-Metal-Catalyzed Sequential C–H Activation/Annulation for One-Step Construction of Functionalized Indazole Derivatives
por: Shiri, Pezhman, et al.
Publicado: (2022)

Annulate lamellae: comparison of antigenic epitopes of annulate lamellae membranes with the nuclear envelope
Publicado: (1988)

Combining Silver Catalysis and Organocatalysis: A Sequential Michael Addition/Hydroalkoxylation One-Pot Approach to Annulated Coumarins
por: Hack, Daniel, et al.
Publicado: (2014)

Mild and Efficient Winterfeldt Oxidation of 1,2,3,4-Tetrahydro-γ-carbolines for the Synthesis of Dihydropyrrolo[3,2-b]-quinolones and Pyrrolo[3,2-b]quinolones
por: Sheng, Rong, et al.
Publicado: (2012)

Structure-Based Design of Orally Bioavailable 1H-Pyrrolo[3,2-c]pyridine Inhibitors of Mitotic Kinase Monopolar Spindle 1 (MPS1)
por: Naud, Sébastien, et al.
Publicado: (2013)

Carbazole Substituted BODIPYs
por: Gupta, Iti, et al.
Publicado: (2019)

8-Methoxy-3,3,5-trimethyl-3,11-dihydropyrano[3,2-a]carbazole
por: Uvarani, C., et al.
Publicado: (2010)

Intramolecular cascade annulation triggered by rhodium(III)-catalyzed sequential C(sp(2))–H activation and C(sp(3))–H amination
por: Song, Liangliang, et al.
Publicado: (2019)

Organophosphine-Catalyzed [4C+X] Annulations
por: Li, Yangyan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8vpdo1no9e9d6r6n4gr0p1lt9i