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A Low Tacrolimus Concentration/Dose Ratio Increases the Risk for the Development of Acute Calcineurin Inhibitor-Induced Nephrotoxicity

Fast tacrolimus metabolism is linked to inferior outcomes such as rejection and lower renal function after kidney transplantation. Renal calcineurin-inhibitor toxicity is a common adverse effect of tacrolimus therapy. The present contribution hypothesized that tacrolimus-induced nephrotoxicity is re...

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Detalles Bibliográficos
Autores principales: Thölking, Gerold, Schütte-Nütgen, Katharina, Schmitz, Julia, Rovas, Alexandros, Dahmen, Maximilian, Bautz, Joachim, Jehn, Ulrich, Pavenstädt, Hermann, Heitplatz, Barbara, Van Marck, Veerle, Suwelack, Barbara, Reuter, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832469/
https://www.ncbi.nlm.nih.gov/pubmed/31581670
http://dx.doi.org/10.3390/jcm8101586

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