Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones

Herein, we report the synthesis of 5,12-dihydropyrazino[2,3-c:5,6-c′]difuro[2,3-c:4,5-c′]-diquinoline-6,14(5H,12H)diones, 2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-1,4-diphenyl- butane-1,4-diones and 4-(benzo-[d]oxazol-2-yl)-3-hydroxy-1H-[4,5]oxazolo[3,2-a]pyridine-1-one. The new candidates were...

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Detalles Bibliográficos
Autores principales: Aly, Ashraf A., Hassan, Alaa A., Mohamed, Nasr K., El-Haleem, Lamiaa E. Abd, Bräse, Stefan, Polamo, Mika, Nieger, Martin, Brown, Alan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832483/
https://www.ncbi.nlm.nih.gov/pubmed/31640196
http://dx.doi.org/10.3390/molecules24203782
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author Aly, Ashraf A.
Hassan, Alaa A.
Mohamed, Nasr K.
El-Haleem, Lamiaa E. Abd
Bräse, Stefan
Polamo, Mika
Nieger, Martin
Brown, Alan B.
author_facet Aly, Ashraf A.
Hassan, Alaa A.
Mohamed, Nasr K.
El-Haleem, Lamiaa E. Abd
Bräse, Stefan
Polamo, Mika
Nieger, Martin
Brown, Alan B.
author_sort Aly, Ashraf A.
collection PubMed
description Herein, we report the synthesis of 5,12-dihydropyrazino[2,3-c:5,6-c′]difuro[2,3-c:4,5-c′]-diquinoline-6,14(5H,12H)diones, 2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-1,4-diphenyl- butane-1,4-diones and 4-(benzo-[d]oxazol-2-yl)-3-hydroxy-1H-[4,5]oxazolo[3,2-a]pyridine-1-one. The new candidates were synthesized and identified by different spectroscopic techniques, and X-ray crystallography.
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spelling pubmed-68324832019-11-25 Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones Aly, Ashraf A. Hassan, Alaa A. Mohamed, Nasr K. El-Haleem, Lamiaa E. Abd Bräse, Stefan Polamo, Mika Nieger, Martin Brown, Alan B. Molecules Article Herein, we report the synthesis of 5,12-dihydropyrazino[2,3-c:5,6-c′]difuro[2,3-c:4,5-c′]-diquinoline-6,14(5H,12H)diones, 2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-1,4-diphenyl- butane-1,4-diones and 4-(benzo-[d]oxazol-2-yl)-3-hydroxy-1H-[4,5]oxazolo[3,2-a]pyridine-1-one. The new candidates were synthesized and identified by different spectroscopic techniques, and X-ray crystallography. MDPI 2019-10-21 /pmc/articles/PMC6832483/ /pubmed/31640196 http://dx.doi.org/10.3390/molecules24203782 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Aly, Ashraf A.
Hassan, Alaa A.
Mohamed, Nasr K.
El-Haleem, Lamiaa E. Abd
Bräse, Stefan
Polamo, Mika
Nieger, Martin
Brown, Alan B.
Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones
title Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones
title_full Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones
title_fullStr Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones
title_full_unstemmed Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones
title_short Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones
title_sort synthesis of new fused heterocyclic 2-quinolones and 3-alkanonyl-4-hydroxy-2-quinolones
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832483/
https://www.ncbi.nlm.nih.gov/pubmed/31640196
http://dx.doi.org/10.3390/molecules24203782
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