TREM-1 Is Upregulated in Experimental Periodontitis, and Its Blockade Inhibits IL-17A and RANKL Expression and Suppresses Bone loss

Aim: Triggering receptor expressed on myeloid cells-1 (TREM-1) is a modifier of local and systemic inflammation. There is clinical evidence implicating TREM-1 in the pathogenesis of periodontitis. However, a cause-and-effect relationship has yet to be demonstrated, as is the underlying mechanism. Th...

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Detalles Bibliográficos
Autores principales: Bostanci, Nagihan, Abe, Toshiharu, Belibasakis, Georgios N., Hajishengallis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832657/
https://www.ncbi.nlm.nih.gov/pubmed/31581596
http://dx.doi.org/10.3390/jcm8101579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832657/
https://www.ncbi.nlm.nih.gov/pubmed/31581596
http://dx.doi.org/10.3390/jcm8101579

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