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Quality of Daily-Life Gait: Novel Outcome for Trials that Focus on Balance, Mobility, and Falls

Technological advances in inertial sensors allow for monitoring of daily-life gait characteristics as a proxy for fall risk. The quality of daily-life gait could serve as a valuable outcome for intervention trials, but the uptake of these measures relies on their power to detect relevant changes in...

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Autores principales: van Schooten, Kimberley S., Pijnappels, Mirjam, Lord, Stephen R., van Dieën, Jaap H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832726/
https://www.ncbi.nlm.nih.gov/pubmed/31614440
http://dx.doi.org/10.3390/s19204388
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author van Schooten, Kimberley S.
Pijnappels, Mirjam
Lord, Stephen R.
van Dieën, Jaap H.
author_facet van Schooten, Kimberley S.
Pijnappels, Mirjam
Lord, Stephen R.
van Dieën, Jaap H.
author_sort van Schooten, Kimberley S.
collection PubMed
description Technological advances in inertial sensors allow for monitoring of daily-life gait characteristics as a proxy for fall risk. The quality of daily-life gait could serve as a valuable outcome for intervention trials, but the uptake of these measures relies on their power to detect relevant changes in fall risk. We collected daily-life gait characteristics in 163 older people (aged 77.5 ± 7.5, 107♀) over two measurement weeks that were two weeks apart. We present variance estimates of daily-life gait characteristics that are sensitive to fall risk and estimate the number of participants required to obtain sufficient statistical power for repeated comparisons. The provided data allows for power analyses for studies using daily-life gait quality as outcome. Our results show that the number of participants required (i.e., 8 to 343 depending on the anticipated effect size and between-measurements correlation) is similar to that generally used in fall prevention trials. We propose that the quality of daily-life gait is a promising outcome for intervention studies that focus on improving balance and mobility and reducing falls.
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spelling pubmed-68327262019-11-25 Quality of Daily-Life Gait: Novel Outcome for Trials that Focus on Balance, Mobility, and Falls van Schooten, Kimberley S. Pijnappels, Mirjam Lord, Stephen R. van Dieën, Jaap H. Sensors (Basel) Article Technological advances in inertial sensors allow for monitoring of daily-life gait characteristics as a proxy for fall risk. The quality of daily-life gait could serve as a valuable outcome for intervention trials, but the uptake of these measures relies on their power to detect relevant changes in fall risk. We collected daily-life gait characteristics in 163 older people (aged 77.5 ± 7.5, 107♀) over two measurement weeks that were two weeks apart. We present variance estimates of daily-life gait characteristics that are sensitive to fall risk and estimate the number of participants required to obtain sufficient statistical power for repeated comparisons. The provided data allows for power analyses for studies using daily-life gait quality as outcome. Our results show that the number of participants required (i.e., 8 to 343 depending on the anticipated effect size and between-measurements correlation) is similar to that generally used in fall prevention trials. We propose that the quality of daily-life gait is a promising outcome for intervention studies that focus on improving balance and mobility and reducing falls. MDPI 2019-10-11 /pmc/articles/PMC6832726/ /pubmed/31614440 http://dx.doi.org/10.3390/s19204388 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
van Schooten, Kimberley S.
Pijnappels, Mirjam
Lord, Stephen R.
van Dieën, Jaap H.
Quality of Daily-Life Gait: Novel Outcome for Trials that Focus on Balance, Mobility, and Falls
title Quality of Daily-Life Gait: Novel Outcome for Trials that Focus on Balance, Mobility, and Falls
title_full Quality of Daily-Life Gait: Novel Outcome for Trials that Focus on Balance, Mobility, and Falls
title_fullStr Quality of Daily-Life Gait: Novel Outcome for Trials that Focus on Balance, Mobility, and Falls
title_full_unstemmed Quality of Daily-Life Gait: Novel Outcome for Trials that Focus on Balance, Mobility, and Falls
title_short Quality of Daily-Life Gait: Novel Outcome for Trials that Focus on Balance, Mobility, and Falls
title_sort quality of daily-life gait: novel outcome for trials that focus on balance, mobility, and falls
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832726/
https://www.ncbi.nlm.nih.gov/pubmed/31614440
http://dx.doi.org/10.3390/s19204388
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