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Dynamics of Phenotypic Heterogeneity Associated with EMT and Stemness during Cancer Progression
Genetic and phenotypic heterogeneity contribute to the generation of diverse tumor cell populations, thus enhancing cancer aggressiveness and therapy resistance. Compared to genetic heterogeneity, a consequence of mutational events, phenotypic heterogeneity arises from dynamic, reversible cell state...
Главные авторы: | , |
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Формат: | Online Статья Текст |
Язык: | English |
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MDPI
2019
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Предметы: | |
Online-ссылка: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832750/ https://www.ncbi.nlm.nih.gov/pubmed/31557977 http://dx.doi.org/10.3390/jcm8101542 |