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Dynamics of Phenotypic Heterogeneity Associated with EMT and Stemness during Cancer Progression

Genetic and phenotypic heterogeneity contribute to the generation of diverse tumor cell populations, thus enhancing cancer aggressiveness and therapy resistance. Compared to genetic heterogeneity, a consequence of mutational events, phenotypic heterogeneity arises from dynamic, reversible cell state...

Полное описание

Библиографические подробности
Главные авторы: Jolly, Mohit Kumar, Celià-Terrassa, Toni
Формат: Online Статья Текст
Язык:English
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832750/
https://www.ncbi.nlm.nih.gov/pubmed/31557977
http://dx.doi.org/10.3390/jcm8101542