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Atomic Force Microscope Guided SERS Spectra Observation for Au@Ag-4MBA@PVP Plasmonic Nanoparticles
Recently polymer encapsulated surface-enhanced-Raman-scattering (SERS) probes with internal noble metal core–shell structure has found growing applications in biomedical applications. Here we studied the SERS spectra of Au@Ag–4MBA@PVP (4MBA: 4-mercaptobenzoic acid; PVP: polyvinylpyrrolidone) plasmon...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833001/ https://www.ncbi.nlm.nih.gov/pubmed/31640276 http://dx.doi.org/10.3390/molecules24203789 |
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author | Yang, Liu Xu, Libei Wu, Xiuju Fang, Hui Zhong, Shenfei Wang, Zhuyuan Bu, Jing Yuan, Xiaocong |
author_facet | Yang, Liu Xu, Libei Wu, Xiuju Fang, Hui Zhong, Shenfei Wang, Zhuyuan Bu, Jing Yuan, Xiaocong |
author_sort | Yang, Liu |
collection | PubMed |
description | Recently polymer encapsulated surface-enhanced-Raman-scattering (SERS) probes with internal noble metal core–shell structure has found growing applications in biomedical applications. Here we studied the SERS spectra of Au@Ag–4MBA@PVP (4MBA: 4-mercaptobenzoic acid; PVP: polyvinylpyrrolidone) plasmonic nanoparticles produced from a chemical reduction method. By linking the atomic force microscope (AFM) with the homebuilt confocal Raman spectrometer thus to use AFM images as guidance, we realized the measurement of the SERS spectra from separated nanoparticles. We investigated the cases for single nanoparticles and for dimer structures and report several observed results including SERS spectra linearly scaled with laser power, abrupt boosting and abnormal shape changing of SERS spectra for dimer structures. Based on the finite element method simulation, we explained the observed ratio of SERS signals between the dimer structure and the single nanoparticle, and attributed the observed abnormal spectra to the photothermal effect of these plasmonic nanoparticles. Our study provides valuable guidance for choosing appropriate laser power when applying similar SERS probes to image biological cells. |
format | Online Article Text |
id | pubmed-6833001 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-68330012019-11-25 Atomic Force Microscope Guided SERS Spectra Observation for Au@Ag-4MBA@PVP Plasmonic Nanoparticles Yang, Liu Xu, Libei Wu, Xiuju Fang, Hui Zhong, Shenfei Wang, Zhuyuan Bu, Jing Yuan, Xiaocong Molecules Article Recently polymer encapsulated surface-enhanced-Raman-scattering (SERS) probes with internal noble metal core–shell structure has found growing applications in biomedical applications. Here we studied the SERS spectra of Au@Ag–4MBA@PVP (4MBA: 4-mercaptobenzoic acid; PVP: polyvinylpyrrolidone) plasmonic nanoparticles produced from a chemical reduction method. By linking the atomic force microscope (AFM) with the homebuilt confocal Raman spectrometer thus to use AFM images as guidance, we realized the measurement of the SERS spectra from separated nanoparticles. We investigated the cases for single nanoparticles and for dimer structures and report several observed results including SERS spectra linearly scaled with laser power, abrupt boosting and abnormal shape changing of SERS spectra for dimer structures. Based on the finite element method simulation, we explained the observed ratio of SERS signals between the dimer structure and the single nanoparticle, and attributed the observed abnormal spectra to the photothermal effect of these plasmonic nanoparticles. Our study provides valuable guidance for choosing appropriate laser power when applying similar SERS probes to image biological cells. MDPI 2019-10-21 /pmc/articles/PMC6833001/ /pubmed/31640276 http://dx.doi.org/10.3390/molecules24203789 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Yang, Liu Xu, Libei Wu, Xiuju Fang, Hui Zhong, Shenfei Wang, Zhuyuan Bu, Jing Yuan, Xiaocong Atomic Force Microscope Guided SERS Spectra Observation for Au@Ag-4MBA@PVP Plasmonic Nanoparticles |
title | Atomic Force Microscope Guided SERS Spectra Observation for Au@Ag-4MBA@PVP Plasmonic Nanoparticles |
title_full | Atomic Force Microscope Guided SERS Spectra Observation for Au@Ag-4MBA@PVP Plasmonic Nanoparticles |
title_fullStr | Atomic Force Microscope Guided SERS Spectra Observation for Au@Ag-4MBA@PVP Plasmonic Nanoparticles |
title_full_unstemmed | Atomic Force Microscope Guided SERS Spectra Observation for Au@Ag-4MBA@PVP Plasmonic Nanoparticles |
title_short | Atomic Force Microscope Guided SERS Spectra Observation for Au@Ag-4MBA@PVP Plasmonic Nanoparticles |
title_sort | atomic force microscope guided sers spectra observation for au@ag-4mba@pvp plasmonic nanoparticles |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833001/ https://www.ncbi.nlm.nih.gov/pubmed/31640276 http://dx.doi.org/10.3390/molecules24203789 |
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