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Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction
BACKGROUND: To compare the outcomes of submucosal tunneling endoscopic resection (STER) and submucosal excavation (ESE) for the treatment of submucosal tumors (SMTs) arising from the muscularis propria (MP) at the esophagogastric junction (EGJ). METHODS: A retrospective analysis of patients with SMT...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833169/ https://www.ncbi.nlm.nih.gov/pubmed/31694564 http://dx.doi.org/10.1186/s12876-019-1099-5 |
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author | Xu, Hong-wei Zhao, Qi Yu, Shu-xia Jiang, Ying Hao, Jing-hua Li, Bin |
author_facet | Xu, Hong-wei Zhao, Qi Yu, Shu-xia Jiang, Ying Hao, Jing-hua Li, Bin |
author_sort | Xu, Hong-wei |
collection | PubMed |
description | BACKGROUND: To compare the outcomes of submucosal tunneling endoscopic resection (STER) and submucosal excavation (ESE) for the treatment of submucosal tumors (SMTs) arising from the muscularis propria (MP) at the esophagogastric junction (EGJ). METHODS: A retrospective analysis of patients with SMTs at EGJ who underwent STER and ESE from October 2011 to October 2017 was performed. The outcomes evaluated were operation time, complete resection rate, adverse events, and tumor recurrence. RESULTS: Ninety patients were included in this study. Complete resection rates in the STER group were higher than those of the ESE group (100 vs. 92%, p < 0.05). For tumors ≤15 mm, both techniques achieved 100% complete resection rate; but for tumors > 15 mm, complete resection rate was higher in the STER group than the ESE group (100% vs. 77.8%, p < 0.05). Subgroup analyses revealed that the operation time of STER for in cardiac-gastric group was longer than that for ESE (145.14 ± 42.43 min vs. 70.32 ± 39.84 min, p < 0.05). The air leakage symptoms were more frequent in STER group (90.9% vs. 50.0%, p < 0.05). No tumor recurrence occurred in both the STER and ESE groups. CONCLUSIONS: For SMTs ≤15 mm, both STER and ESE have similar satisfactory therapeutic outcomes. However, in the cardiac-gastric subgroup, STER had a longer operative time compared to the ESE procedure. For SMTs > 15 mm, STER is the preferred choice due to its higher complete resection rate. |
format | Online Article Text |
id | pubmed-6833169 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-68331692019-11-08 Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction Xu, Hong-wei Zhao, Qi Yu, Shu-xia Jiang, Ying Hao, Jing-hua Li, Bin BMC Gastroenterol Research Article BACKGROUND: To compare the outcomes of submucosal tunneling endoscopic resection (STER) and submucosal excavation (ESE) for the treatment of submucosal tumors (SMTs) arising from the muscularis propria (MP) at the esophagogastric junction (EGJ). METHODS: A retrospective analysis of patients with SMTs at EGJ who underwent STER and ESE from October 2011 to October 2017 was performed. The outcomes evaluated were operation time, complete resection rate, adverse events, and tumor recurrence. RESULTS: Ninety patients were included in this study. Complete resection rates in the STER group were higher than those of the ESE group (100 vs. 92%, p < 0.05). For tumors ≤15 mm, both techniques achieved 100% complete resection rate; but for tumors > 15 mm, complete resection rate was higher in the STER group than the ESE group (100% vs. 77.8%, p < 0.05). Subgroup analyses revealed that the operation time of STER for in cardiac-gastric group was longer than that for ESE (145.14 ± 42.43 min vs. 70.32 ± 39.84 min, p < 0.05). The air leakage symptoms were more frequent in STER group (90.9% vs. 50.0%, p < 0.05). No tumor recurrence occurred in both the STER and ESE groups. CONCLUSIONS: For SMTs ≤15 mm, both STER and ESE have similar satisfactory therapeutic outcomes. However, in the cardiac-gastric subgroup, STER had a longer operative time compared to the ESE procedure. For SMTs > 15 mm, STER is the preferred choice due to its higher complete resection rate. BioMed Central 2019-11-06 /pmc/articles/PMC6833169/ /pubmed/31694564 http://dx.doi.org/10.1186/s12876-019-1099-5 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Xu, Hong-wei Zhao, Qi Yu, Shu-xia Jiang, Ying Hao, Jing-hua Li, Bin Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction |
title | Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction |
title_full | Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction |
title_fullStr | Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction |
title_full_unstemmed | Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction |
title_short | Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction |
title_sort | comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833169/ https://www.ncbi.nlm.nih.gov/pubmed/31694564 http://dx.doi.org/10.1186/s12876-019-1099-5 |
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