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miR-149-3p reverses CD8(+) T-cell exhaustion by reducing inhibitory receptors and promoting cytokine secretion in breast cancer cells

Blockade of inhibitory receptors (IRs) is one of the most effective immunotherapeutic approaches to treat cancer. Dysfunction of miRNAs is a major cause of aberrant expression of IRs and contributes to the immune escape of cancer cells. How miRNAs regulate immune checkpoint proteins in breast cancer...

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Detalles Bibliográficos
Autores principales:	Zhang, Meng, Gao, Dian, Shi, Yanmei, Wang, Yifan, Joshi, Rakesh, Yu, Qiongfang, Liu, Daheng, Alotaibi, Faizah, Zhang, Yujuan, Wang, Hongmei, Li, Qing, Zhang, Zhu-Xu, Koropatnick, James, Min, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833224/ https://www.ncbi.nlm.nih.gov/pubmed/31594465 http://dx.doi.org/10.1098/rsob.190061

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