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Increase of reactive oxygen species contributes to growth inhibition by fluconazole in Cryptococcus neoformans

BACKGROUND: Cryptococcus neoformans, a basidiomycetous yeast, is a fungal pathogen that can colonize the lungs of humans causing pneumonia and fungal meningitis in severely immunocompromised individuals. Recent studies have implied that the antifungal drug fluconazole (FLC) can induce oxidative stre...

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Detalles Bibliográficos
Autores principales: Dbouk, Nadir Hani, Covington, Madison Bailey, Nguyen, Kenny, Chandrasekaran, Srikripa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833255/
https://www.ncbi.nlm.nih.gov/pubmed/31694529
http://dx.doi.org/10.1186/s12866-019-1606-4