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Development of molecular and pharmacological switches for chimeric antigen receptor T cells

The use of chimeric antigen receptor (CAR) T cell technology as a therapeutic strategy for the treatment blood-born human cancers has delivered outstanding clinical efficacy. However, this treatment modality can also be associated with serious adverse events in the form of cytokine release syndrome....

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Detalles Bibliográficos
Autores principales: Wu, Bill X., Song, No-Joon, Riesenberg, Brian P., Li, Zihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833279/
https://www.ncbi.nlm.nih.gov/pubmed/31709128
http://dx.doi.org/10.1186/s40164-019-0151-z

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