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Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report
A 73-year-old-male patient with hypertension and grade 3B chronic kidney disease underwent radical nephrectomy in the year 2000. As the renal function gradually worsened, the patient was started on hemodialysis in 2003. Eleven years after nephrectomy, the metastases were pointed out. The patient rec...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833355/ https://www.ncbi.nlm.nih.gov/pubmed/31709150 http://dx.doi.org/10.1016/j.eucr.2019.101048 |
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author | Ito, Akito Hisano, Mizuki Takahashi, Makoto Komine, Naoki Abe, Takaya Obara, Wataru |
author_facet | Ito, Akito Hisano, Mizuki Takahashi, Makoto Komine, Naoki Abe, Takaya Obara, Wataru |
author_sort | Ito, Akito |
collection | PubMed |
description | A 73-year-old-male patient with hypertension and grade 3B chronic kidney disease underwent radical nephrectomy in the year 2000. As the renal function gradually worsened, the patient was started on hemodialysis in 2003. Eleven years after nephrectomy, the metastases were pointed out. The patient received sunitinib as first-line therapy. Thereafter, as the metastatic lesions became larger, we initiated nivolumab therapy (3 mg/m2 every 2 weeks). After 52 weeks, the metastatic lesions continued showing complete response (CR). No adverse effects were observed during nivolumab treatment. |
format | Online Article Text |
id | pubmed-6833355 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-68333552019-11-08 Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report Ito, Akito Hisano, Mizuki Takahashi, Makoto Komine, Naoki Abe, Takaya Obara, Wataru Urol Case Rep Oncology A 73-year-old-male patient with hypertension and grade 3B chronic kidney disease underwent radical nephrectomy in the year 2000. As the renal function gradually worsened, the patient was started on hemodialysis in 2003. Eleven years after nephrectomy, the metastases were pointed out. The patient received sunitinib as first-line therapy. Thereafter, as the metastatic lesions became larger, we initiated nivolumab therapy (3 mg/m2 every 2 weeks). After 52 weeks, the metastatic lesions continued showing complete response (CR). No adverse effects were observed during nivolumab treatment. Elsevier 2019-10-15 /pmc/articles/PMC6833355/ /pubmed/31709150 http://dx.doi.org/10.1016/j.eucr.2019.101048 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Oncology Ito, Akito Hisano, Mizuki Takahashi, Makoto Komine, Naoki Abe, Takaya Obara, Wataru Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report |
title | Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report |
title_full | Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report |
title_fullStr | Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report |
title_full_unstemmed | Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report |
title_short | Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report |
title_sort | complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833355/ https://www.ncbi.nlm.nih.gov/pubmed/31709150 http://dx.doi.org/10.1016/j.eucr.2019.101048 |
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