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Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report

A 73-year-old-male patient with hypertension and grade 3B chronic kidney disease underwent radical nephrectomy in the year 2000. As the renal function gradually worsened, the patient was started on hemodialysis in 2003. Eleven years after nephrectomy, the metastases were pointed out. The patient rec...

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Detalles Bibliográficos
Autores principales: Ito, Akito, Hisano, Mizuki, Takahashi, Makoto, Komine, Naoki, Abe, Takaya, Obara, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833355/
https://www.ncbi.nlm.nih.gov/pubmed/31709150
http://dx.doi.org/10.1016/j.eucr.2019.101048
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author Ito, Akito
Hisano, Mizuki
Takahashi, Makoto
Komine, Naoki
Abe, Takaya
Obara, Wataru
author_facet Ito, Akito
Hisano, Mizuki
Takahashi, Makoto
Komine, Naoki
Abe, Takaya
Obara, Wataru
author_sort Ito, Akito
collection PubMed
description A 73-year-old-male patient with hypertension and grade 3B chronic kidney disease underwent radical nephrectomy in the year 2000. As the renal function gradually worsened, the patient was started on hemodialysis in 2003. Eleven years after nephrectomy, the metastases were pointed out. The patient received sunitinib as first-line therapy. Thereafter, as the metastatic lesions became larger, we initiated nivolumab therapy (3 mg/m2 every 2 weeks). After 52 weeks, the metastatic lesions continued showing complete response (CR). No adverse effects were observed during nivolumab treatment.
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spelling pubmed-68333552019-11-08 Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report Ito, Akito Hisano, Mizuki Takahashi, Makoto Komine, Naoki Abe, Takaya Obara, Wataru Urol Case Rep Oncology A 73-year-old-male patient with hypertension and grade 3B chronic kidney disease underwent radical nephrectomy in the year 2000. As the renal function gradually worsened, the patient was started on hemodialysis in 2003. Eleven years after nephrectomy, the metastases were pointed out. The patient received sunitinib as first-line therapy. Thereafter, as the metastatic lesions became larger, we initiated nivolumab therapy (3 mg/m2 every 2 weeks). After 52 weeks, the metastatic lesions continued showing complete response (CR). No adverse effects were observed during nivolumab treatment. Elsevier 2019-10-15 /pmc/articles/PMC6833355/ /pubmed/31709150 http://dx.doi.org/10.1016/j.eucr.2019.101048 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Ito, Akito
Hisano, Mizuki
Takahashi, Makoto
Komine, Naoki
Abe, Takaya
Obara, Wataru
Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report
title Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report
title_full Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report
title_fullStr Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report
title_full_unstemmed Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report
title_short Complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report
title_sort complete response to nivolumab for metastatic renal cell carcinoma on hemodialysis patient; a case report
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833355/
https://www.ncbi.nlm.nih.gov/pubmed/31709150
http://dx.doi.org/10.1016/j.eucr.2019.101048
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