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Relationship between Helicobacter pylori-positivity in the gallbladder and stomach and effect on gallbladder pathologies
OBJECTIVE: Helicobacter pylori commonly occurs in the stomach, but localizations outside the stomach and related diseases have also been investigated. However, the relationship between H. pylori and gallstones remains controversial. We aimed to investigate the relationships between H. pylori in the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833382/ https://www.ncbi.nlm.nih.gov/pubmed/31434515 http://dx.doi.org/10.1177/0300060519847345 |
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author | Ari, Aziz Tatar, Cihad Yarikkaya, Enver |
author_facet | Ari, Aziz Tatar, Cihad Yarikkaya, Enver |
author_sort | Ari, Aziz |
collection | PubMed |
description | OBJECTIVE: Helicobacter pylori commonly occurs in the stomach, but localizations outside the stomach and related diseases have also been investigated. However, the relationship between H. pylori and gallstones remains controversial. We aimed to investigate the relationships between H. pylori in the stomach and the gallbladder and gallstones. METHODS: This prospective case-control study included patients who underwent cholecystectomy because of gallstones, pancreatic head cancer, or hepatic resection. The patients were separated into two groups according to the detection of H. pylori in gallbladder samples using Giemsa staining. Stomach H. pylori status was based on previous gastroscopy. RESULTS: The study enrolled 60 patients, comprising 27 patients with gallstones and 33 without. There was no significant difference in the incidence of gallstones between patients with or without H. pylori in the stomach or gallbladder. Furthermore, the presence of H. pylori in the stomach was measured in 14 patients and was significantly correlated with H. pylori in the gallbladder. CONCLUSION: The current study showed no relationship between the occurrence of gallstones and the presence of H. pylori in either the gallbladder or the stomach. In contrast to previous reports, this suggests that H. pylori does not play a role in the development of gallstones. |
format | Online Article Text |
id | pubmed-6833382 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-68333822019-11-13 Relationship between Helicobacter pylori-positivity in the gallbladder and stomach and effect on gallbladder pathologies Ari, Aziz Tatar, Cihad Yarikkaya, Enver J Int Med Res Clinical Research Reports OBJECTIVE: Helicobacter pylori commonly occurs in the stomach, but localizations outside the stomach and related diseases have also been investigated. However, the relationship between H. pylori and gallstones remains controversial. We aimed to investigate the relationships between H. pylori in the stomach and the gallbladder and gallstones. METHODS: This prospective case-control study included patients who underwent cholecystectomy because of gallstones, pancreatic head cancer, or hepatic resection. The patients were separated into two groups according to the detection of H. pylori in gallbladder samples using Giemsa staining. Stomach H. pylori status was based on previous gastroscopy. RESULTS: The study enrolled 60 patients, comprising 27 patients with gallstones and 33 without. There was no significant difference in the incidence of gallstones between patients with or without H. pylori in the stomach or gallbladder. Furthermore, the presence of H. pylori in the stomach was measured in 14 patients and was significantly correlated with H. pylori in the gallbladder. CONCLUSION: The current study showed no relationship between the occurrence of gallstones and the presence of H. pylori in either the gallbladder or the stomach. In contrast to previous reports, this suggests that H. pylori does not play a role in the development of gallstones. SAGE Publications 2019-08-22 2019-10 /pmc/articles/PMC6833382/ /pubmed/31434515 http://dx.doi.org/10.1177/0300060519847345 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Clinical Research Reports Ari, Aziz Tatar, Cihad Yarikkaya, Enver Relationship between Helicobacter pylori-positivity in the gallbladder and stomach and effect on gallbladder pathologies |
title | Relationship between Helicobacter pylori-positivity in the gallbladder and stomach and effect on gallbladder pathologies |
title_full | Relationship between Helicobacter pylori-positivity in the gallbladder and stomach and effect on gallbladder pathologies |
title_fullStr | Relationship between Helicobacter pylori-positivity in the gallbladder and stomach and effect on gallbladder pathologies |
title_full_unstemmed | Relationship between Helicobacter pylori-positivity in the gallbladder and stomach and effect on gallbladder pathologies |
title_short | Relationship between Helicobacter pylori-positivity in the gallbladder and stomach and effect on gallbladder pathologies |
title_sort | relationship between helicobacter pylori-positivity in the gallbladder and stomach and effect on gallbladder pathologies |
topic | Clinical Research Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833382/ https://www.ncbi.nlm.nih.gov/pubmed/31434515 http://dx.doi.org/10.1177/0300060519847345 |
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