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A combination of ultrasonic debridement and Shenghong wet dressing in patients with chronic ulcers of the lower limbs

OBJECTIVE: This study aimed to examine the effects of ultrasonic debridement plus a wet dressing of Shenghong (SH) on chronic ulcer healing of the lower extremities in patients with diabetes. METHODS: Sixty cases of diabetes combined with chronic lower limb ulcers were randomly divided into control...

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Autores principales: Xiaolan, Xie, Wujie, Guan, Xiaoyan, Tang, Wenlai, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833434/
https://www.ncbi.nlm.nih.gov/pubmed/31469017
http://dx.doi.org/10.1177/0300060519858033
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author Xiaolan, Xie
Wujie, Guan
Xiaoyan, Tang
Wenlai, Chang
author_facet Xiaolan, Xie
Wujie, Guan
Xiaoyan, Tang
Wenlai, Chang
author_sort Xiaolan, Xie
collection PubMed
description OBJECTIVE: This study aimed to examine the effects of ultrasonic debridement plus a wet dressing of Shenghong (SH) on chronic ulcer healing of the lower extremities in patients with diabetes. METHODS: Sixty cases of diabetes combined with chronic lower limb ulcers were randomly divided into control (n = 30) and experimental (n = 30) groups. The control group was treated with ultrasonic debridement plus recombinant human fibroblast growth factor (FGF) gel. The experimental group was treated with ultrasonic debridement plus SH wet dressing. RESULTS: The mean clinical efficacy in the experimental group was significantly higher than that in the control group (93.33% ± 6.32% versus 60.0% ± 5.87%). The mean ulcer area was significantly smaller and the mean ulcer healing rate was significantly shorter in the first 3 months, and the mean overall pain intensity score was significantly lower in the experimental group than in the control group. Moreover, the positive rates of bacterial culture on the 7(th) and 15(th) days were significantly lower in the experimental group than in the control group. CONCLUSION: The use of ultrasonic debridement plus SH wet dressing for treating ulcers can significantly improve clinical efficacy and promote healing.
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spelling pubmed-68334342019-11-13 A combination of ultrasonic debridement and Shenghong wet dressing in patients with chronic ulcers of the lower limbs Xiaolan, Xie Wujie, Guan Xiaoyan, Tang Wenlai, Chang J Int Med Res Clinical Research Reports OBJECTIVE: This study aimed to examine the effects of ultrasonic debridement plus a wet dressing of Shenghong (SH) on chronic ulcer healing of the lower extremities in patients with diabetes. METHODS: Sixty cases of diabetes combined with chronic lower limb ulcers were randomly divided into control (n = 30) and experimental (n = 30) groups. The control group was treated with ultrasonic debridement plus recombinant human fibroblast growth factor (FGF) gel. The experimental group was treated with ultrasonic debridement plus SH wet dressing. RESULTS: The mean clinical efficacy in the experimental group was significantly higher than that in the control group (93.33% ± 6.32% versus 60.0% ± 5.87%). The mean ulcer area was significantly smaller and the mean ulcer healing rate was significantly shorter in the first 3 months, and the mean overall pain intensity score was significantly lower in the experimental group than in the control group. Moreover, the positive rates of bacterial culture on the 7(th) and 15(th) days were significantly lower in the experimental group than in the control group. CONCLUSION: The use of ultrasonic debridement plus SH wet dressing for treating ulcers can significantly improve clinical efficacy and promote healing. SAGE Publications 2019-08-30 2019-10 /pmc/articles/PMC6833434/ /pubmed/31469017 http://dx.doi.org/10.1177/0300060519858033 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Clinical Research Reports
Xiaolan, Xie
Wujie, Guan
Xiaoyan, Tang
Wenlai, Chang
A combination of ultrasonic debridement and Shenghong wet dressing in patients with chronic ulcers of the lower limbs
title A combination of ultrasonic debridement and Shenghong wet dressing in patients with chronic ulcers of the lower limbs
title_full A combination of ultrasonic debridement and Shenghong wet dressing in patients with chronic ulcers of the lower limbs
title_fullStr A combination of ultrasonic debridement and Shenghong wet dressing in patients with chronic ulcers of the lower limbs
title_full_unstemmed A combination of ultrasonic debridement and Shenghong wet dressing in patients with chronic ulcers of the lower limbs
title_short A combination of ultrasonic debridement and Shenghong wet dressing in patients with chronic ulcers of the lower limbs
title_sort combination of ultrasonic debridement and shenghong wet dressing in patients with chronic ulcers of the lower limbs
topic Clinical Research Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833434/
https://www.ncbi.nlm.nih.gov/pubmed/31469017
http://dx.doi.org/10.1177/0300060519858033
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