Voltage vs. Ligand I: Structural basis of the intrinsic flexibility of S3 segment and its significance in ion channel activation

We systematically predict the internal flexibility of the S3 segment, one of the most mobile elements in the voltage-sensor domain. By analyzing the primary amino acid sequences of V-sensor containing proteins, including Hv1, TPC channels and the voltage-sensing phosphatases, we established correlat...

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Detalles Bibliográficos
Autores principales: Balleza, Daniel, Rosas, Mario E., Romero-Romero, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833973/
https://www.ncbi.nlm.nih.gov/pubmed/31647368
http://dx.doi.org/10.1080/19336950.2019.1674242

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