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Systematic screening of 96 Schistosoma mansoni cell-surface and secreted antigens does not identify any strongly protective vaccine candidates in a mouse model of infection
Background: Schistosomiasis is a major parasitic disease affecting people living in tropical and sup-tropical areas. Transmission of the parasite has been reported in 78 countries, causing significant morbidity and around 200,000 deaths per year in endemic regions. The disease is currently managed b...
Autores principales: | Crosnier, Cecile, Brandt, Cordelia, Rinaldi, Gabriel, McCarthy, Catherine, Barker, Colin, Clare, Simon, Berriman, Matthew, Wright, Gavin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833992/ https://www.ncbi.nlm.nih.gov/pubmed/31728414 http://dx.doi.org/10.12688/wellcomeopenres.15487.1 |
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