Mixed-Generation PAMAM G3-G0 Megamer as a Drug Delivery System for Nimesulide: Antitumor Activity of the Conjugate Against Human Squamous Carcinoma and Glioblastoma Cells

Polyhydroxylated dendrimer was synthesized from poly(amidoamine) (PAMAM) dendrimer generation 3 by addition of glycidol (G3(gl)). G3(gl) megamer was further modified by binding PAMAM G0 dendrimers by activation of G3(gl) with p-nitrophenylchloroformate, followed by the addition of excess PAMAM G0 an...

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Detalles Bibliográficos
Autores principales: Zaręba, Magdalena, Sareło, Przemysław, Kopaczyńska, Marta, Białońska, Agata, Uram, Łukasz, Walczak, Małgorzata, Aebisher, David, Wołowiec, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834146/
https://www.ncbi.nlm.nih.gov/pubmed/31601050
http://dx.doi.org/10.3390/ijms20204998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834146/
https://www.ncbi.nlm.nih.gov/pubmed/31601050
http://dx.doi.org/10.3390/ijms20204998

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