Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence

Lymph nodes (LN) and their resident T follicular helper CD4+ T cells (Tfh) are a critical site for HIV replication and persistence. Therefore, optimizing antiviral activity in lymphoid tissues will be needed to reduce or eliminate the HIV reservoir. In this study, we retained effector immune cells i...

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Detalles Bibliográficos
Autores principales: Pino, Maria, Paganini, Sara, Deleage, Claire, Padhan, Kartika, Harper, Justin L., King, Colin T., Micci, Luca, Cervasi, Barbara, Mudd, Joseph C., Gill, Kiran P., Jean, Sherrie M., Easley, Kirk, Silvestri, Guido, Estes, Jacob D., Petrovas, Constantinos, Lederman, Michael M., Paiardini, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834281/
https://www.ncbi.nlm.nih.gov/pubmed/31626660
http://dx.doi.org/10.1371/journal.ppat.1008081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834281/
https://www.ncbi.nlm.nih.gov/pubmed/31626660
http://dx.doi.org/10.1371/journal.ppat.1008081

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