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Inducible Cardiac-Specific Deletion of Sirt1 in Male Mice Reveals Progressive Cardiac Dysfunction and Sensitization of the Heart to Pressure Overload

Heart failure is associated with profound alterations of energy metabolism thought to play a major role in the progression of this syndrome. SIRT1 is a metabolic sensor of cellular energy and exerts essential functions on energy metabolism, oxidative stress response, apoptosis, or aging. Importantly...

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Detalles Bibliográficos
Autores principales:	Sanz, Maria-Nieves, Grimbert, Lucile, Moulin, Maryline, Gressette, Mélanie, Rucker-Martin, Catherine, Lemaire, Christophe, Mericskay, Mathias, Veksler, Vladimir, Ventura-Clapier, Renée, Garnier, Anne, Piquereau, Jérôme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834316/ https://www.ncbi.nlm.nih.gov/pubmed/31658614 http://dx.doi.org/10.3390/ijms20205005

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