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Chronic BDE-47 Exposure Aggravates Malignant Phenotypes and Chemoresistance by Activating ERK Through ERα and GPR30 in Endometrial Carcinoma

Environmental exposure to certain compounds contribute to cell plasticity, tumor progression and even chemoresistance. 2,2′,4,4′-tetrabromo diphenyl ether (BDE-47), one of the most frequently detected polybrominated diphenyl ethers (PBDEs) in environmental and biological samples, is a known estrogen...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Peng, Lin, Huang, Yiteng, Lin, Xueqiong, Zhou, Li, Chen, Jiongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834531/
https://www.ncbi.nlm.nih.gov/pubmed/31737560
http://dx.doi.org/10.3389/fonc.2019.01079