Cargando…

NHE5 regulates growth factor signaling, integrin trafficking, and degradation in glioma cells

Na(+)/H(+) exchanger 5 (NHE5) is enriched in neurons and cycles between recycling endosomes and plasma membranes and transports protons to the endosomal lumen as well as to the extracellular space. Although NHE5 expression is undetectable in normal astrocytes, C6 glioma cells express NHE5 at an elev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kurata, Toru, Rajendran, Vinotheni, Fan, Steven, Ohta, Tetsuo, Numata, Masayuki, Fushida, Sachio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834540/ https://www.ncbi.nlm.nih.gov/pubmed/31595389 http://dx.doi.org/10.1007/s10585-019-10001-6

Ejemplares similares

Endosomal Na(+)/H(+) exchanger NHE5 influences MET recycling and cell migration
por: Fan, Steven Hung-Yi, et al.
Publicado: (2016)

Endosomal acidification by Na(+)/H(+) exchanger NHE5 regulates TrkA cell-surface targeting and NGF-induced PI3K signaling
por: Diering, Graham H., et al.
Publicado: (2013)

Endosomal pH in neuronal signaling and synaptic transmission: role of Na(+)/H(+) exchanger NHE5
por: Diering, Graham H., et al.
Publicado: (2014)

Low-dose eribulin mesylate exerts antitumor effects in gastric cancer by inhibiting fibrosis via the suppression of epithelial–mesenchymal transition and acts synergistically with 5-fluorouracil
por: Kurata, Toru, et al.
Publicado: (2018)

Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na(+)/H(+) exchanger NHE5
por: Diering, Graham H., et al.
Publicado: (2011)

Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3
por: Singh, Varsha, et al.
Publicado: (2015)

Thoracoscopic radical esophagectomy and laparoscopic transhiatal lymph node dissection for superficial esophageal cancer associated with lymph node metastases in the dorsal area of the thoracic aorta
por: Ninomiya, Itasu, et al.
Publicado: (2015)

Genes for endosomal NHE6 and NHE9 are misregulated in autism brains
por: Schwede, M, et al.
Publicado: (2014)

Integrin Trafficking and Tumor Progression
por: Shin, Sejeong, et al.
Publicado: (2012)

Importance of human peritoneal mesothelial cells in the progression, fibrosis, and control of gastric cancer: inhibition of growth and fibrosis by tranilast
por: Saito, Hiroto, et al.
Publicado: (2017)

Phosphorylation of NHE3-S(719) regulates NHE3 activity through the formation of multiple signaling complexes
por: Sarker, Rafiquel, et al.
Publicado: (2017)

Paclitaxel plus valproic acid versus paclitaxel alone as second- or third-line therapy for advanced gastric cancer: a randomized Phase II trial
por: Fushida, Sachio, et al.
Publicado: (2016)

Multidisciplinary therapy for scirrhous gastric cancer: a retrospective analysis and proposal of new treatment strategy
por: Fushida, Sachio, et al.
Publicado: (2018)

The mammalian Na+/H+ antiporters NHE-1, NHE-2, and NHE-3 are electroneutral and voltage independent, but can couple to an H+ conductance
Publicado: (1995)

Complex Formation between NheB and NheC Is Necessary to Induce Cytotoxic Activity by the Three-Component Bacillus cereus Nhe Enterotoxin
por: Heilkenbrinker, Uta, et al.
Publicado: (2013)

Integrin-Linked Kinase Links Integrin Activation to Invadopodia Function and Invasion via the p(T567)-Ezrin/NHERF1/NHE1 Pathway
por: Greco, Maria Raffaella, et al.
Publicado: (2021)

Structure of the NheA Component of the Nhe Toxin from Bacillus cereus: Implications for Function
por: Ganash, Magdah, et al.
Publicado: (2013)

Role of NHE1 in Nociception
por: Torres-López, Jorge Elías, et al.
Publicado: (2013)

Blocking NHE1 stimulates glioma tumor immunity by restoring OXPHOS function of myeloid cells
por: Hasan, Md Nabiul, et al.
Publicado: (2021)

Pioglitazone inhibits the proliferation and metastasis of human pancreatic cancer cells
por: NINOMIYA, ITASU, et al.
Publicado: (2014)

VEGF is a target molecule for peritoneal metastasis and malignant ascites in gastric cancer: prognostic significance of VEGF in ascites and efficacy of anti-VEGF monoclonal antibody
por: Fushida, Sachio, et al.
Publicado: (2013)

Treatment of capecitabine-induced hand-foot syndrome using a topical retinoid: A case report
por: INOKUCHI, MASAFUMI, et al.
Publicado: (2014)

Establishing a xenograft mouse model of peritoneal dissemination of gastric cancer with organ invasion and fibrosis
por: Okazaki, Mitsuyoshi, et al.
Publicado: (2017)

Antitumor and anti-metastatic effects of cyclooxygenase-2 inhibition by celecoxib on human colorectal carcinoma xenografts in nude mouse rectum
por: NINOMIYA, ITASU, et al.
Publicado: (2012)

The effect of HIF-1α and PKM1 expression on acquisition of chemoresistance
por: Okazaki, Mitsuyoshi, et al.
Publicado: (2018)

Incidence of and risk factors for totally implantable vascular access device complications in patients with gastric cancer: A retrospective analysis
por: Okazaki, Mitsuyoshi, et al.
Publicado: (2019)

Integrin Inhibitor Suppresses Bevacizumab-Induced Glioma Invasion()()
por: Ishida, Joji, et al.
Publicado: (2014)

Pyrazine ring-based Na(+)/H(+) exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1
por: Rolver, Michala G., et al.
Publicado: (2020)

A Case of Severe Sepsis Presenting Marked Decrease of Neutrophils and Interesting Findings on Dynamic CT
por: Makino, Isamu, et al.
Publicado: (2015)

Potential of extravasated platelet aggregation as a surrogate marker for overall survival in patients with advanced gastric cancer treated with preoperative docetaxel, cisplatin and S-1: a retrospective observational study
por: Saito, Hiroto, et al.
Publicado: (2017)

Peripheral Blood Platelet–Lymphocyte Ratio Is Good Predictor of Chemosensitivity and Prognosis in Gastric Cancer Patients
por: Ohe, Yuka, et al.
Publicado: (2020)

Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report
por: Okazaki, Mitsuyoshi, et al.
Publicado: (2020)

Rainbow Trout (Oncorhynchus mykiss) Na(+)/H(+) Exchangers tNhe3a and tNhe3b Display Unique Inhibitory Profiles Dissimilar from Mammalian NHE Isoforms
por: Blair, Salvatore, et al.
Publicado: (2021)

Integrating intracellular nanovesicles into integrin trafficking pathways and beyond
por: Larocque, Gabrielle, et al.
Publicado: (2022)

Distinct integrin activation pathways for effector and regulatory T cell trafficking and function
por: Sun, Hao, et al.
Publicado: (2020)

Loss of Christianson Syndrome Na(+)/H(+) Exchanger 6 (NHE6) Causes Abnormal Endosome Maturation and Trafficking Underlying Lysosome Dysfunction in Neurons
por: Pescosolido, Matthew F., et al.
Publicado: (2021)

The role of human peritoneal mesothelial cells in the fibrosis and progression of gastric cancer
por: TSUKADA, TOMOYA, et al.
Publicado: (2012)

Low-dose paclitaxel modulates tumour fibrosis in gastric cancer
por: TSUKADA, TOMOYA, et al.
Publicado: (2013)

Randomized Phase II trial of paclitaxel plus valproic acid vs paclitaxel alone as second-line therapy for patients with advanced gastric cancer
por: Fushida, Sachio, et al.
Publicado: (2015)

Interleukin-17A derived from mast cells contributes to fibrosis in gastric cancer with peritoneal dissemination
por: Gunjigake, Katsuya, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_59esedkhabugg8njf70c0comto