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Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington’s disease

Huntington’s disease (HD) is a fatal inherited autosomal dominant neurodegenerative disorder caused by an expansion in the number of CAG trinucleotide repeats in the huntingtin gene. The disease is characterized by motor, behavioural and cognitive symptoms for which at present there are no disease a...

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Detalles Bibliográficos
Autores principales:	Irvine, Elaine E., Katsouri, Loukia, Plattner, Florian, Al-Qassab, Hind, Al-Nackkash, Rand, Bates, Gillian P., Withers, Dominic J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834565/ https://www.ncbi.nlm.nih.gov/pubmed/31695068 http://dx.doi.org/10.1038/s41598-019-52391-3

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