Extracellular vesicles from endothelial progenitor cells prevent steroid-induced osteoporosis by suppressing the ferroptotic pathway in mouse osteoblasts based on bioinformatics evidence

Abnormal antioxidative capabilities were observed in the pathogenesis of steroid-induced osteoporosis (SIOP). Ferroptosis is a recently discovered type of cell death that is characterized by the overproduction of ROS in response to GPX4 and system X(c−) downregulation, which is mediated by an Fe(2+)...

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Detalles Bibliográficos
Autores principales: Lu, Jinsen, Yang, Jiazhao, Zheng, Yongshun, Chen, Xiaoyu, Fang, Shiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834614/
https://www.ncbi.nlm.nih.gov/pubmed/31695092
http://dx.doi.org/10.1038/s41598-019-52513-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834614/
https://www.ncbi.nlm.nih.gov/pubmed/31695092
http://dx.doi.org/10.1038/s41598-019-52513-x

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