Global transcriptome analysis of rat hypothalamic arcuate nucleus demonstrates reversal of hypothalamic gliosis following surgically and diet induced weight loss

The central mechanisms underlying the marked beneficial metabolic effects of bariatric surgery are unclear. Here, we characterized global gene expression in the hypothalamic arcuate nucleus (Arc) in diet-induced obese (DIO) rats following Roux-en-Y gastric bypass (RYGB). 60 days post-RYGB, the Arc w...

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Detalles Bibliográficos
Autores principales: Barkholt, Pernille, Rigbolt, Kristoffer T. G., Falkenhahn, Mechthilde, Hübschle, Thomas, Schwahn, Uwe, Fernandez-Cachon, Maria Luisa, Schmidt, Thorsten, Theis, Stefan, Hansen, Henrik H., Hay-Schmidt, Anders, Pedersen, Philip J., Vrang, Niels, Jelsing, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834618/
https://www.ncbi.nlm.nih.gov/pubmed/31695063
http://dx.doi.org/10.1038/s41598-019-52257-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834618/
https://www.ncbi.nlm.nih.gov/pubmed/31695063
http://dx.doi.org/10.1038/s41598-019-52257-8

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