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Fat cadherins in mouse models of degenerative ataxias
Autophagy is a lysosomal degradation pathway that plays an essential role in neuronal homeostasis and is perturbed in many neurological diseases. Transcriptional downregulation of fat was previously observed in a Drosophila model of the polyglutamine disease Dentatorubral-pallidoluysian atrophy (DRP...
Autores principales: | Baron, Olga, Grieshober, Denise, Dias, Catarina, Fanto, Manolis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834631/ https://www.ncbi.nlm.nih.gov/pubmed/31695130 http://dx.doi.org/10.1038/s41598-019-52684-7 |
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