miR-223 overexpression inhibits doxorubicin-induced autophagy by targeting FOXO3a and reverses chemoresistance in hepatocellular carcinoma cells

Doxorubicin is conventionally used in chemotherapy against hepatocellular carcinoma (HCC), but acquired resistance developed during long-term therapy limits its benefits. Autophagy, a conserved catabolic process for cellular self-protection and adaptation to the changing environment, is regarded as...

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Detalles Bibliográficos
Autores principales: Zhou, Yue, Chen, Enjiang, Tang, Yuexiao, Mao, Jiayan, Shen, Jian, Zheng, Xiaoxiao, Xie, Shangzhi, Zhang, Shufen, Wu, Ying, Liu, Hao, Zhi, Xiao, Ma, Tao, Ni, Haibin, Chen, Jiabin, Chai, Kequn, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834650/
https://www.ncbi.nlm.nih.gov/pubmed/31695022
http://dx.doi.org/10.1038/s41419-019-2053-8

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