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Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells
The main purpose of this study was to suggest a solution for inflammation caused by urban daily life based on supercritical extraction of Chamaecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Alpha-pinene, anti-...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Exercise Rehabilitation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834702/ https://www.ncbi.nlm.nih.gov/pubmed/31723563 http://dx.doi.org/10.12965/jer.1938442.221 |
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author | Kwak, Byeong Mun Kim, Ee-Hwa Kim, Yong-Min Kim, Hee-Tack |
author_facet | Kwak, Byeong Mun Kim, Ee-Hwa Kim, Yong-Min Kim, Hee-Tack |
author_sort | Kwak, Byeong Mun |
collection | PubMed |
description | The main purpose of this study was to suggest a solution for inflammation caused by urban daily life based on supercritical extraction of Chamaecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Alpha-pinene, anti-inflammatory active compound of C. obtusa, was analyzed by electrospray ionization-mass spectrometry, gas chromatography, and gas chromatography mass spectrometry from each part of extracts. As a result of the reduction rate of nitric oxide in RAW 264.7 cells, the wood extract exhibited the highest reduction rate was about 45% among extracts from four part of C. obtusa. The wood extract from C. obtusa can be developed as a good anti-inflammatory natural raw material for natural product industry. |
format | Online Article Text |
id | pubmed-6834702 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Korean Society of Exercise Rehabilitation |
record_format | MEDLINE/PubMed |
spelling | pubmed-68347022019-11-13 Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells Kwak, Byeong Mun Kim, Ee-Hwa Kim, Yong-Min Kim, Hee-Tack J Exerc Rehabil Original Article The main purpose of this study was to suggest a solution for inflammation caused by urban daily life based on supercritical extraction of Chamaecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Alpha-pinene, anti-inflammatory active compound of C. obtusa, was analyzed by electrospray ionization-mass spectrometry, gas chromatography, and gas chromatography mass spectrometry from each part of extracts. As a result of the reduction rate of nitric oxide in RAW 264.7 cells, the wood extract exhibited the highest reduction rate was about 45% among extracts from four part of C. obtusa. The wood extract from C. obtusa can be developed as a good anti-inflammatory natural raw material for natural product industry. Korean Society of Exercise Rehabilitation 2019-10-28 /pmc/articles/PMC6834702/ /pubmed/31723563 http://dx.doi.org/10.12965/jer.1938442.221 Text en Copyright © 2019 Korean Society of Exercise Rehabilitation This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kwak, Byeong Mun Kim, Ee-Hwa Kim, Yong-Min Kim, Hee-Tack Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells |
title | Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells |
title_full | Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells |
title_fullStr | Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells |
title_full_unstemmed | Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells |
title_short | Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells |
title_sort | component analysis of four-part extracts from chamaecyparis obtusa endl. by supercritical fluid extraction and anti-inflammatory effect on raw 264.7cells |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834702/ https://www.ncbi.nlm.nih.gov/pubmed/31723563 http://dx.doi.org/10.12965/jer.1938442.221 |
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