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Angiopoietin-Like 3: From Discovery to Therapeutic Gene Editing
Hyperlipidemia is a major causal risk factor for atherosclerosis and coronary heart disease (CHD). Angiopoietin-like 3 (ANGPTL3) has emerged as a promising molecular target to reduce CHD risk due to its regulation of all 3 major lipid traits: low-density lipoprotein cholesterol, high-density lipopro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834959/ https://www.ncbi.nlm.nih.gov/pubmed/31709322 http://dx.doi.org/10.1016/j.jacbts.2019.05.008 |