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Improved Modeling of Peptide-Protein Binding Through Global Docking and Accelerated Molecular Dynamics Simulations

Peptides mediate up to 40% of known protein-protein interactions in higher eukaryotes and play a key role in cellular signaling, protein trafficking, immunology, and oncology. However, it is challenging to predict peptide-protein binding with conventional computational modeling approaches, due to sl...

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Detalles Bibliográficos
Autores principales:	Wang, Jinan, Alekseenko, Andrey, Kozakov, Dima, Miao, Yinglong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835073/ https://www.ncbi.nlm.nih.gov/pubmed/31737642 http://dx.doi.org/10.3389/fmolb.2019.00112

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