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4 Ds in health research—working together toward rapid precision medicine

Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre‐existing disease condition. Therapy remains predominantly symptom‐based, although it is increasingly clear that individual treatment is possible...

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Detalles Bibliográficos
Autores principales: Niederberger, Ellen, Parnham, Michael J, Maas, Jochen, Geisslinger, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835200/
https://www.ncbi.nlm.nih.gov/pubmed/31531943
http://dx.doi.org/10.15252/emmm.201910917
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author Niederberger, Ellen
Parnham, Michael J
Maas, Jochen
Geisslinger, Gerd
author_facet Niederberger, Ellen
Parnham, Michael J
Maas, Jochen
Geisslinger, Gerd
author_sort Niederberger, Ellen
collection PubMed
description Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre‐existing disease condition. Therapy remains predominantly symptom‐based, although it is increasingly clear that individual treatment is possible and beneficial. However, reasonable precision medicine can only be realized with the coordinated use of diagnostics, devices and drugs in combination with extensive databases (4Ds), an approach that has not yet found sufficient implementation. The practical combination of 4Ds in health care is progressing, but several obstacles still hamper their extended use in precision medicine.
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spelling pubmed-68352002019-11-08 4 Ds in health research—working together toward rapid precision medicine Niederberger, Ellen Parnham, Michael J Maas, Jochen Geisslinger, Gerd EMBO Mol Med Commentary Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre‐existing disease condition. Therapy remains predominantly symptom‐based, although it is increasingly clear that individual treatment is possible and beneficial. However, reasonable precision medicine can only be realized with the coordinated use of diagnostics, devices and drugs in combination with extensive databases (4Ds), an approach that has not yet found sufficient implementation. The practical combination of 4Ds in health care is progressing, but several obstacles still hamper their extended use in precision medicine. John Wiley and Sons Inc. 2019-09-18 2019-11-07 /pmc/articles/PMC6835200/ /pubmed/31531943 http://dx.doi.org/10.15252/emmm.201910917 Text en © 2019 The Authors. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Niederberger, Ellen
Parnham, Michael J
Maas, Jochen
Geisslinger, Gerd
4 Ds in health research—working together toward rapid precision medicine
title 4 Ds in health research—working together toward rapid precision medicine
title_full 4 Ds in health research—working together toward rapid precision medicine
title_fullStr 4 Ds in health research—working together toward rapid precision medicine
title_full_unstemmed 4 Ds in health research—working together toward rapid precision medicine
title_short 4 Ds in health research—working together toward rapid precision medicine
title_sort 4 ds in health research—working together toward rapid precision medicine
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835200/
https://www.ncbi.nlm.nih.gov/pubmed/31531943
http://dx.doi.org/10.15252/emmm.201910917
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