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4 Ds in health research—working together toward rapid precision medicine
Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre‐existing disease condition. Therapy remains predominantly symptom‐based, although it is increasingly clear that individual treatment is possible...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835200/ https://www.ncbi.nlm.nih.gov/pubmed/31531943 http://dx.doi.org/10.15252/emmm.201910917 |
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author | Niederberger, Ellen Parnham, Michael J Maas, Jochen Geisslinger, Gerd |
author_facet | Niederberger, Ellen Parnham, Michael J Maas, Jochen Geisslinger, Gerd |
author_sort | Niederberger, Ellen |
collection | PubMed |
description | Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre‐existing disease condition. Therapy remains predominantly symptom‐based, although it is increasingly clear that individual treatment is possible and beneficial. However, reasonable precision medicine can only be realized with the coordinated use of diagnostics, devices and drugs in combination with extensive databases (4Ds), an approach that has not yet found sufficient implementation. The practical combination of 4Ds in health care is progressing, but several obstacles still hamper their extended use in precision medicine. |
format | Online Article Text |
id | pubmed-6835200 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-68352002019-11-08 4 Ds in health research—working together toward rapid precision medicine Niederberger, Ellen Parnham, Michael J Maas, Jochen Geisslinger, Gerd EMBO Mol Med Commentary Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre‐existing disease condition. Therapy remains predominantly symptom‐based, although it is increasingly clear that individual treatment is possible and beneficial. However, reasonable precision medicine can only be realized with the coordinated use of diagnostics, devices and drugs in combination with extensive databases (4Ds), an approach that has not yet found sufficient implementation. The practical combination of 4Ds in health care is progressing, but several obstacles still hamper their extended use in precision medicine. John Wiley and Sons Inc. 2019-09-18 2019-11-07 /pmc/articles/PMC6835200/ /pubmed/31531943 http://dx.doi.org/10.15252/emmm.201910917 Text en © 2019 The Authors. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Commentary Niederberger, Ellen Parnham, Michael J Maas, Jochen Geisslinger, Gerd 4 Ds in health research—working together toward rapid precision medicine |
title | 4 Ds in health research—working together toward rapid precision medicine |
title_full | 4 Ds in health research—working together toward rapid precision medicine |
title_fullStr | 4 Ds in health research—working together toward rapid precision medicine |
title_full_unstemmed | 4 Ds in health research—working together toward rapid precision medicine |
title_short | 4 Ds in health research—working together toward rapid precision medicine |
title_sort | 4 ds in health research—working together toward rapid precision medicine |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835200/ https://www.ncbi.nlm.nih.gov/pubmed/31531943 http://dx.doi.org/10.15252/emmm.201910917 |
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