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Enrichment of Antigen-Specific Class-Switched B Cells from Individuals Naturally Immunized by Infection with Group A Streptococcus

The low frequency of circulating antigen-specific memory B cells is a considerable obstacle in the discovery and development of human monoclonal antibodies for therapeutic application. Here, we evaluate two solid-phase isolation methods to enrich the number of antigen-specific B cells from individua...

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Detalles Bibliográficos
Autores principales:	Lamb, Cheri L., Price, Emily, Field, Kevin P., Dayton, Christopher, McIndoo, Eric R., Katahira, Eva J., Stevens, Dennis L., Hobdey, Sarah E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835209/ https://www.ncbi.nlm.nih.gov/pubmed/31694896 http://dx.doi.org/10.1128/mSphere.00598-19

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