Fluorescein- and EGFR-Antibody Conjugated Silica Nanoparticles for Enhancement of Real-time Tumor Border Definition Using Confocal Laser Endomicroscopy in Squamous Cell Carcinoma of the Head and Neck

Intraoperative definition of tumor free resection margins in head and neck cancer is challenging. In the current proof-of-principle study we evaluated a novel silica nanoparticle-based agent for its potential use as contrast enhancer. We synthesized silica nanoparticles with an average size of 45 nm...

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Detalles Bibliográficos
Autores principales: Watermann, Anna, Gieringer, Rita, Bauer, Anna-Maria, Kurch, Sven, Kiesslich, Ralf, Tremel, Wolfgang, Gosepath, Jan, Brieger, Juergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835239/
https://www.ncbi.nlm.nih.gov/pubmed/31561451
http://dx.doi.org/10.3390/nano9101378

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