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Enzymes from Marine Polar Regions and Their Biotechnological Applications

The microorganisms that evolved at low temperatures express cold-adapted enzymes endowed with unique catalytic properties in comparison to their mesophilic homologues, i.e., higher catalytic efficiency, improved flexibility, and lower thermal stability. Cold environments are therefore an attractive...

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Autores principales: Bruno, Stefano, Coppola, Daniela, di Prisco, Guido, Giordano, Daniela, Verde, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835263/
https://www.ncbi.nlm.nih.gov/pubmed/31547548
http://dx.doi.org/10.3390/md17100544
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author Bruno, Stefano
Coppola, Daniela
di Prisco, Guido
Giordano, Daniela
Verde, Cinzia
author_facet Bruno, Stefano
Coppola, Daniela
di Prisco, Guido
Giordano, Daniela
Verde, Cinzia
author_sort Bruno, Stefano
collection PubMed
description The microorganisms that evolved at low temperatures express cold-adapted enzymes endowed with unique catalytic properties in comparison to their mesophilic homologues, i.e., higher catalytic efficiency, improved flexibility, and lower thermal stability. Cold environments are therefore an attractive research area for the discovery of enzymes to be used for investigational and industrial applications in which such properties are desirable. In this work, we will review the literature on cold-adapted enzymes specifically focusing on those discovered in the bioprospecting of polar marine environments, so far largely neglected because of their limited accessibility. We will discuss their existing or proposed biotechnological applications within the framework of the more general applications of cold-adapted enzymes.
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spelling pubmed-68352632019-11-25 Enzymes from Marine Polar Regions and Their Biotechnological Applications Bruno, Stefano Coppola, Daniela di Prisco, Guido Giordano, Daniela Verde, Cinzia Mar Drugs Review The microorganisms that evolved at low temperatures express cold-adapted enzymes endowed with unique catalytic properties in comparison to their mesophilic homologues, i.e., higher catalytic efficiency, improved flexibility, and lower thermal stability. Cold environments are therefore an attractive research area for the discovery of enzymes to be used for investigational and industrial applications in which such properties are desirable. In this work, we will review the literature on cold-adapted enzymes specifically focusing on those discovered in the bioprospecting of polar marine environments, so far largely neglected because of their limited accessibility. We will discuss their existing or proposed biotechnological applications within the framework of the more general applications of cold-adapted enzymes. MDPI 2019-09-23 /pmc/articles/PMC6835263/ /pubmed/31547548 http://dx.doi.org/10.3390/md17100544 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bruno, Stefano
Coppola, Daniela
di Prisco, Guido
Giordano, Daniela
Verde, Cinzia
Enzymes from Marine Polar Regions and Their Biotechnological Applications
title Enzymes from Marine Polar Regions and Their Biotechnological Applications
title_full Enzymes from Marine Polar Regions and Their Biotechnological Applications
title_fullStr Enzymes from Marine Polar Regions and Their Biotechnological Applications
title_full_unstemmed Enzymes from Marine Polar Regions and Their Biotechnological Applications
title_short Enzymes from Marine Polar Regions and Their Biotechnological Applications
title_sort enzymes from marine polar regions and their biotechnological applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835263/
https://www.ncbi.nlm.nih.gov/pubmed/31547548
http://dx.doi.org/10.3390/md17100544
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