Effect of Polymer Permeability and Solvent Removal Rate on In Situ Forming Implants: Drug Burst Release and Microstructure

To explore the mechanism of drug release and depot formation of in situ forming implants (ISFIs), osthole-loaded ISFIs were prepared by dissolving polylactide, poly(lactide-co-glycolide), polycaprolactone, or poly(trimethylene carbonate) in different organic solvents, including N-methyl-2-pyrrolidon...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaowei, Yang, Liqun, Zhang, Chong, Liu, Danhua, Meng, Shu, Zhang, Wei, Meng, Shengnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835277/
https://www.ncbi.nlm.nih.gov/pubmed/31658642
http://dx.doi.org/10.3390/pharmaceutics11100520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835277/
https://www.ncbi.nlm.nih.gov/pubmed/31658642
http://dx.doi.org/10.3390/pharmaceutics11100520

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