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Effect of Polymer Permeability and Solvent Removal Rate on In Situ Forming Implants: Drug Burst Release and Microstructure
To explore the mechanism of drug release and depot formation of in situ forming implants (ISFIs), osthole-loaded ISFIs were prepared by dissolving polylactide, poly(lactide-co-glycolide), polycaprolactone, or poly(trimethylene carbonate) in different organic solvents, including N-methyl-2-pyrrolidon...
Autores principales: | Zhang, Xiaowei, Yang, Liqun, Zhang, Chong, Liu, Danhua, Meng, Shu, Zhang, Wei, Meng, Shengnan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835277/ https://www.ncbi.nlm.nih.gov/pubmed/31658642 http://dx.doi.org/10.3390/pharmaceutics11100520 |
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