Lipid droplet‐dependent fatty acid metabolism controls the immune suppressive phenotype of tumor‐associated macrophages

Tumor‐associated macrophages (TAMs) promote tumor growth and metastasis by suppressing tumor immune surveillance. Herein, we provide evidence that the immunosuppressive phenotype of TAMs is controlled by long‐chain fatty acid metabolism, specifically unsaturated fatty acids, here exemplified by olea...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Han, Yijie, Rodriguez Sillke, Yasmina, Deng, Hongzhang, Siddiqui, Sophiya, Treese, Christoph, Schmidt, Franziska, Friedrich, Marie, Keye, Jacqueline, Wan, Jiajia, Qin, Yue, Kühl, Anja A, Qin, Zhihai, Siegmund, Britta, Glauben, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835560/
https://www.ncbi.nlm.nih.gov/pubmed/31602788
http://dx.doi.org/10.15252/emmm.201910698

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