In Vivo Microdialysis of Endogenous and (13)C-labeled TCA Metabolites in Rat Brain: Reversible and Persistent Effects of Mitochondrial Inhibition and Transient Cerebral Ischemia

Cerebral micro-dialysis allows continuous sampling of extracellular metabolites, including glucose, lactate and pyruvate. Transient ischemic events cause a rapid drop in glucose and a rise in lactate levels. Following such events, the lactate/pyruvate (L/P) ratio may remain elevated for a prolonged...

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Detalles Bibliográficos
Autores principales: Havelund, Jesper F., Nygaard, Kevin H., Nielsen, Troels H., Nordström, Carl-Henrik, Poulsen, Frantz R., Færgeman, Nils. J., Forsse, Axel, Gramsbergen, Jan Bert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835622/
https://www.ncbi.nlm.nih.gov/pubmed/31569792
http://dx.doi.org/10.3390/metabo9100204

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