Cargando…

Griffithsin, a Highly Potent Broad-Spectrum Antiviral Lectin from Red Algae: From Discovery to Clinical Application

Virus entry into a susceptible host cell is the first step in the formation of all viral diseases. Controlling viral infections by disrupting viral entry is advantageous for antibody-mediated neutralization by the host’s immune system and as a preventive and therapeutic antiviral strategy. Recently,...

Descripción completa

Detalles Bibliográficos
Autor principal:	Lee, Choongho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835697/ https://www.ncbi.nlm.nih.gov/pubmed/31590428 http://dx.doi.org/10.3390/md17100567

Ejemplares similares

Novel Antifungal Activity of Q-Griffithsin, a Broad-Spectrum Antiviral Lectin
por: Nabeta, Henry W., et al.
Publicado: (2021)

Bulk production of the antiviral lectin griffithsin
por: Fuqua, Joshua L., et al.
Publicado: (2015)

Griffithsin: An Antiviral Lectin with Outstanding Therapeutic Potential
por: Lusvarghi, Sabrina, et al.
Publicado: (2016)

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus
por: Moulaei, Tinoush, et al.
Publicado: (2015)

Discovery of Potent Broad Spectrum Antivirals Derived from Marine Actinobacteria
por: Raveh, Avi, et al.
Publicado: (2013)

Pharmacokinetics of the Antiviral Lectin Griffithsin Administered by Different Routes Indicates Multiple Potential Uses
por: Barton, Christopher, et al.
Publicado: (2016)

Antiviral lectin Q-Griffithsin suppresses fungal infection in murine models of vaginal candidiasis
por: Nabeta, Henry W., et al.
Publicado: (2022)

Antiviral Lectins from Red and Blue-Green Algae Show Potent In Vitro and In Vivo Activity against Hepatitis C Virus
por: Takebe, Yutaka, et al.
Publicado: (2013)

Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding
por: Ziółkowska, Natasza E., et al.
Publicado: (2006)

Lectins from red algae and their biomedical potential
por: Singh, Ram Sarup, et al.
Publicado: (2017)

Characterization of the hypersensitive response‐like cell death phenomenon induced by targeting antiviral lectin griffithsin to the secretory pathway
por: Kim, Bo Min, et al.
Publicado: (2018)

Characterization of a Novel Mannose-Binding Lectin with Antiviral Activities from Red Alga, Grateloupia chiangii
por: Hwang, Hyun-Ju, et al.
Publicado: (2020)

Low-Cost, Large-Scale Production of the Anti-viral Lectin Griffithsin
por: Decker, John S., et al.
Publicado: (2020)

An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo
por: Zhao, Yajing, et al.
Publicado: (2022)

Grifonin-1: A Small HIV-1 Entry Inhibitor Derived from the Algal Lectin, Griffithsin
por: Micewicz, Ewa D., et al.
Publicado: (2010)

Integrated autolysis, DNA hydrolysis and precipitation enables an improved bioprocess for Q-Griffithsin, a broad-spectrum antiviral and clinical-stage anti-COVID-19 candidate
por: Decker, John S., et al.
Publicado: (2022)

Carrageenans as Broad-Spectrum Microbicides: Current Status and Challenges
por: Lee, Choongho
Publicado: (2020)

A Potent, Broad-Spectrum Antiviral Agent that Targets Viral Membranes
por: Wojcechowskyj, Jason A., et al.
Publicado: (2010)

Crystallographic studies of the complexes of antiviral protein griffithsin with glucose and N-acetylglucosamine
por: Ziółkowska, Natasza E., et al.
Publicado: (2007)

In vitro antiviral activity of Griffithsin against porcine epidemic diarrhea virus
por: Li, Lan, et al.
Publicado: (2019)

Discovery and development of safe-in-man broad-spectrum antiviral agents
por: Andersen, Petter I., et al.
Publicado: (2020)

Clofazimine derivatives as potent broad-spectrum antiviral agents with dual-target mechanism
por: Zhang, Xintong, et al.
Publicado: (2022)

High mannose-specific lectin (KAA-2) from the red alga Kappaphycus alvarezii potently inhibits influenza virus infection in a strain-independent manner
por: Sato, Yuichiro, et al.
Publicado: (2011)

Broad Spectrum Algae Compounds Against Viruses
por: Reis, Jacqueline Graff, et al.
Publicado: (2022)

Rice endosperm is cost‐effective for the production of recombinant griffithsin with potent activity against HIV
por: Vamvaka, Evangelia, et al.
Publicado: (2016)

Discovery of sex in an extremophilic red alga
por: Goodenough, Ursula
Publicado: (2022)

Broad-Spectrum Antiviral Therapeutics
por: Rider, Todd H., et al.
Publicado: (2011)

Broad-spectrum antiviral agents
por: Zhu, Jun-Da, et al.
Publicado: (2015)

Structure and anticancer activity of a new lectin from the cultivated red alga, Kappaphycus striatus
por: Hung, Le Dinh, et al.
Publicado: (2020)

Broad-Spectrum Antivirals and Antiviral Drug Combinations
por: Oksenych, Valentyn, et al.
Publicado: (2022)

Broad-Spectrum Antivirals Derived from Natural Products
por: Tian, Wen-Jun, et al.
Publicado: (2023)

Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity
por: Gondim, Ana C. S., et al.
Publicado: (2019)

A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses
por: Zhao, Hanjun, et al.
Publicado: (2016)

Characterization of Isoforms of the Lectin Isolated from the Red Algae Bryothamnion seaforthii and Its Pro-Healing Effect
por: do Nascimento-Neto, Luiz Gonzaga, et al.
Publicado: (2012)

Broad-Spectrum Antivirals and Antiviral Combinations: An Editorial Update
por: Kainov, Denis, et al.
Publicado: (2022)

Valorization of the Red Algae Gelidium sesquipedale by Extracting a Broad Spectrum of Minor Compounds Using Green Approaches
por: Castejón, Natalia, et al.
Publicado: (2021)

Modified cyclodextrins as broad-spectrum antivirals
por: Jones, Samuel T., et al.
Publicado: (2020)

Small Molecule Antiviral Compound Collection (SMACC): a database to support the discovery of broad-spectrum antiviral drug molecules
por: Martin, Holli-Joi, et al.
Publicado: (2022)

Mannose-Binding Lectins as Potent Antivirals against SARS-CoV-2
por: Grosche, Victória Riquena, et al.
Publicado: (2023)

Griffithsin with A Broad-Spectrum Antiviral Activity by Binding Glycans in Viral Glycoprotein Exhibits Strong Synergistic Effect in Combination with A Pan-Coronavirus Fusion Inhibitor Targeting SARS-CoV-2 Spike S2 Subunit
por: Cai, Yanxing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kd1vse6indvhiiq2pasgufcpnr