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Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors
Introduction: The use of medication has increased in recent years in the US while the use of dietary supplements has remained stable but high. Interactions between these two kinds of products may have important consequences, especially in the case of widely used medications such as antihypertensives...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835757/ https://www.ncbi.nlm.nih.gov/pubmed/31618867 http://dx.doi.org/10.3390/nu11102466 |
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author | Aznar-Lou, Ignacio Carbonell-Duacastella, Cristina Rodriguez, Ana Mera, Inés Rubio-Valera, Maria |
author_facet | Aznar-Lou, Ignacio Carbonell-Duacastella, Cristina Rodriguez, Ana Mera, Inés Rubio-Valera, Maria |
author_sort | Aznar-Lou, Ignacio |
collection | PubMed |
description | Introduction: The use of medication has increased in recent years in the US while the use of dietary supplements has remained stable but high. Interactions between these two kinds of products may have important consequences, especially in the case of widely used medications such as antihypertensives and antibiotics. The aim of this paper is to estimate the prevalence of potentially serious drug–dietary supplement interactions among tetracyclines, thiazides, and angiotensin II receptor blocker users by means of the NHANES 2013–2014 dataset. Methods: Data from 2013–2014 NHANES were obtained. Potential interactions analysed were tetracyclines with calcium, magnesium, and zinc, thiazides with vitamin D, and angiotensin II receptors blockers with potassium. Prevalence was calculated for each potential interaction. Logistic regression was used to assess associated factors. Results: 864 prescriptions issued to 820 patients were analysed. Overall prevalence of potential interaction was 49%. Older age and higher educational level were strongly associated with being at risk of a potential interaction. Factors such as age, race, civil status, citizenship, country of birth, BMI, and physical activity did not show notable associations. Conclusions: Healthcare professionals should be aware of other medical products when they prescribe or dispense a medication or a dietary supplement, especially to the older population and people with a higher educational level. |
format | Online Article Text |
id | pubmed-6835757 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-68357572019-11-25 Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors Aznar-Lou, Ignacio Carbonell-Duacastella, Cristina Rodriguez, Ana Mera, Inés Rubio-Valera, Maria Nutrients Article Introduction: The use of medication has increased in recent years in the US while the use of dietary supplements has remained stable but high. Interactions between these two kinds of products may have important consequences, especially in the case of widely used medications such as antihypertensives and antibiotics. The aim of this paper is to estimate the prevalence of potentially serious drug–dietary supplement interactions among tetracyclines, thiazides, and angiotensin II receptor blocker users by means of the NHANES 2013–2014 dataset. Methods: Data from 2013–2014 NHANES were obtained. Potential interactions analysed were tetracyclines with calcium, magnesium, and zinc, thiazides with vitamin D, and angiotensin II receptors blockers with potassium. Prevalence was calculated for each potential interaction. Logistic regression was used to assess associated factors. Results: 864 prescriptions issued to 820 patients were analysed. Overall prevalence of potential interaction was 49%. Older age and higher educational level were strongly associated with being at risk of a potential interaction. Factors such as age, race, civil status, citizenship, country of birth, BMI, and physical activity did not show notable associations. Conclusions: Healthcare professionals should be aware of other medical products when they prescribe or dispense a medication or a dietary supplement, especially to the older population and people with a higher educational level. MDPI 2019-10-15 /pmc/articles/PMC6835757/ /pubmed/31618867 http://dx.doi.org/10.3390/nu11102466 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Aznar-Lou, Ignacio Carbonell-Duacastella, Cristina Rodriguez, Ana Mera, Inés Rubio-Valera, Maria Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors |
title | Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors |
title_full | Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors |
title_fullStr | Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors |
title_full_unstemmed | Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors |
title_short | Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors |
title_sort | prevalence of medication-dietary supplement combined use and associated factors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835757/ https://www.ncbi.nlm.nih.gov/pubmed/31618867 http://dx.doi.org/10.3390/nu11102466 |
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