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Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors

Introduction: The use of medication has increased in recent years in the US while the use of dietary supplements has remained stable but high. Interactions between these two kinds of products may have important consequences, especially in the case of widely used medications such as antihypertensives...

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Autores principales: Aznar-Lou, Ignacio, Carbonell-Duacastella, Cristina, Rodriguez, Ana, Mera, Inés, Rubio-Valera, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835757/
https://www.ncbi.nlm.nih.gov/pubmed/31618867
http://dx.doi.org/10.3390/nu11102466
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author Aznar-Lou, Ignacio
Carbonell-Duacastella, Cristina
Rodriguez, Ana
Mera, Inés
Rubio-Valera, Maria
author_facet Aznar-Lou, Ignacio
Carbonell-Duacastella, Cristina
Rodriguez, Ana
Mera, Inés
Rubio-Valera, Maria
author_sort Aznar-Lou, Ignacio
collection PubMed
description Introduction: The use of medication has increased in recent years in the US while the use of dietary supplements has remained stable but high. Interactions between these two kinds of products may have important consequences, especially in the case of widely used medications such as antihypertensives and antibiotics. The aim of this paper is to estimate the prevalence of potentially serious drug–dietary supplement interactions among tetracyclines, thiazides, and angiotensin II receptor blocker users by means of the NHANES 2013–2014 dataset. Methods: Data from 2013–2014 NHANES were obtained. Potential interactions analysed were tetracyclines with calcium, magnesium, and zinc, thiazides with vitamin D, and angiotensin II receptors blockers with potassium. Prevalence was calculated for each potential interaction. Logistic regression was used to assess associated factors. Results: 864 prescriptions issued to 820 patients were analysed. Overall prevalence of potential interaction was 49%. Older age and higher educational level were strongly associated with being at risk of a potential interaction. Factors such as age, race, civil status, citizenship, country of birth, BMI, and physical activity did not show notable associations. Conclusions: Healthcare professionals should be aware of other medical products when they prescribe or dispense a medication or a dietary supplement, especially to the older population and people with a higher educational level.
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spelling pubmed-68357572019-11-25 Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors Aznar-Lou, Ignacio Carbonell-Duacastella, Cristina Rodriguez, Ana Mera, Inés Rubio-Valera, Maria Nutrients Article Introduction: The use of medication has increased in recent years in the US while the use of dietary supplements has remained stable but high. Interactions between these two kinds of products may have important consequences, especially in the case of widely used medications such as antihypertensives and antibiotics. The aim of this paper is to estimate the prevalence of potentially serious drug–dietary supplement interactions among tetracyclines, thiazides, and angiotensin II receptor blocker users by means of the NHANES 2013–2014 dataset. Methods: Data from 2013–2014 NHANES were obtained. Potential interactions analysed were tetracyclines with calcium, magnesium, and zinc, thiazides with vitamin D, and angiotensin II receptors blockers with potassium. Prevalence was calculated for each potential interaction. Logistic regression was used to assess associated factors. Results: 864 prescriptions issued to 820 patients were analysed. Overall prevalence of potential interaction was 49%. Older age and higher educational level were strongly associated with being at risk of a potential interaction. Factors such as age, race, civil status, citizenship, country of birth, BMI, and physical activity did not show notable associations. Conclusions: Healthcare professionals should be aware of other medical products when they prescribe or dispense a medication or a dietary supplement, especially to the older population and people with a higher educational level. MDPI 2019-10-15 /pmc/articles/PMC6835757/ /pubmed/31618867 http://dx.doi.org/10.3390/nu11102466 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Aznar-Lou, Ignacio
Carbonell-Duacastella, Cristina
Rodriguez, Ana
Mera, Inés
Rubio-Valera, Maria
Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors
title Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors
title_full Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors
title_fullStr Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors
title_full_unstemmed Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors
title_short Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors
title_sort prevalence of medication-dietary supplement combined use and associated factors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835757/
https://www.ncbi.nlm.nih.gov/pubmed/31618867
http://dx.doi.org/10.3390/nu11102466
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