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Characterization of the Noncanonical Regulatory and Transporter Genes in Atratumycin Biosynthesis and Production in a Heterologous Host

Atratumycin is a cyclodepsipeptide with activity against Mycobacteria tuberculosis isolated from deep-sea derived Streptomyces atratus SCSIO ZH16NS-80S. Analysis of the atratumycin biosynthetic gene cluster (atr) revealed that its biosynthesis is regulated by multiple factors, including two LuxR reg...

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Detalles Bibliográficos
Autores principales:	Yang, Zhijie, Wei, Xin, He, Jianqiao, Sun, Changli, Ju, Jianhua, Ma, Junying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835768/ https://www.ncbi.nlm.nih.gov/pubmed/31569487 http://dx.doi.org/10.3390/md17100560

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