Cargando…
Effects of Long-Versus Short-Term Exposure to the Mediterranean Diet on Skin Microvascular Function and Quality of Life of Healthy Adults in Greece and the UK
The beneficial effects of the Mediterranean diet (MD) adherence in reducing cardiovascular disease (CVD) risk and improving CVD-related physiological indices have been well-documented. However, the exact MD adherence duration needed for these effects to occur is under-researched. The aim of the pres...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835788/ https://www.ncbi.nlm.nih.gov/pubmed/31623223 http://dx.doi.org/10.3390/nu11102487 |
_version_ | 1783466755622961152 |
---|---|
author | Klonizakis, Markos Grammatikopoulou, Maria G. Theodoridis, Xenophon Milner, Marianne Liu, Yingshan Chourdakis, Michael |
author_facet | Klonizakis, Markos Grammatikopoulou, Maria G. Theodoridis, Xenophon Milner, Marianne Liu, Yingshan Chourdakis, Michael |
author_sort | Klonizakis, Markos |
collection | PubMed |
description | The beneficial effects of the Mediterranean diet (MD) adherence in reducing cardiovascular disease (CVD) risk and improving CVD-related physiological indices have been well-documented. However, the exact MD adherence duration needed for these effects to occur is under-researched. The aim of the present, two-arm, two-site study clinical trial was to assess the effects of long- vs. short-term MD adherence on the skin microvascular circulation, and quality of life. Two groups were recruited, one being long-term MD adherers (>5 years; from Greece; control group), and one of the non-adherers (from the UK), with the latter participating in a four-week MD intervention (intervention group). Our main outcome was skin microvascular function assessed by cutaneous vascular conductance (CVC). Secondary outcomes included quality of life, dietary intake, blood pressure and lipidemic profile. At the end of the intervention, both groups had high MD adherence. For the intervention group, significantly improved post-intervention CVC values were noted concerning the initial peak phase (2.0 ± 0.6 vs. 2.8 ± 0.8; p < 0.05). CVC values of the control group, were however higher at the plateau phase in comparison to the intervention group (intervention end; 3.8 ± 0.8 vs. 3.1 ± 1.2; p < 0.05). As per QoL, the physical domain was improved post-intervention (13.7 ± 1.2 vs. 15.9 ± 1.2; p < 0.05). No differences were observed in the lipidemic profile between groups, or between the baseline and final intervention phases. The findings indicate that although short-term MD adherence is effective in improving certain microvascular physiological properties and QoL domains, there is room for additional improvement, observed in long-term adherers. Our findings are important in the design of future, MD-based, lifestyle interventions, with the advisable durations differing between target groups. |
format | Online Article Text |
id | pubmed-6835788 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-68357882019-11-25 Effects of Long-Versus Short-Term Exposure to the Mediterranean Diet on Skin Microvascular Function and Quality of Life of Healthy Adults in Greece and the UK Klonizakis, Markos Grammatikopoulou, Maria G. Theodoridis, Xenophon Milner, Marianne Liu, Yingshan Chourdakis, Michael Nutrients Article The beneficial effects of the Mediterranean diet (MD) adherence in reducing cardiovascular disease (CVD) risk and improving CVD-related physiological indices have been well-documented. However, the exact MD adherence duration needed for these effects to occur is under-researched. The aim of the present, two-arm, two-site study clinical trial was to assess the effects of long- vs. short-term MD adherence on the skin microvascular circulation, and quality of life. Two groups were recruited, one being long-term MD adherers (>5 years; from Greece; control group), and one of the non-adherers (from the UK), with the latter participating in a four-week MD intervention (intervention group). Our main outcome was skin microvascular function assessed by cutaneous vascular conductance (CVC). Secondary outcomes included quality of life, dietary intake, blood pressure and lipidemic profile. At the end of the intervention, both groups had high MD adherence. For the intervention group, significantly improved post-intervention CVC values were noted concerning the initial peak phase (2.0 ± 0.6 vs. 2.8 ± 0.8; p < 0.05). CVC values of the control group, were however higher at the plateau phase in comparison to the intervention group (intervention end; 3.8 ± 0.8 vs. 3.1 ± 1.2; p < 0.05). As per QoL, the physical domain was improved post-intervention (13.7 ± 1.2 vs. 15.9 ± 1.2; p < 0.05). No differences were observed in the lipidemic profile between groups, or between the baseline and final intervention phases. The findings indicate that although short-term MD adherence is effective in improving certain microvascular physiological properties and QoL domains, there is room for additional improvement, observed in long-term adherers. Our findings are important in the design of future, MD-based, lifestyle interventions, with the advisable durations differing between target groups. MDPI 2019-10-16 /pmc/articles/PMC6835788/ /pubmed/31623223 http://dx.doi.org/10.3390/nu11102487 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Klonizakis, Markos Grammatikopoulou, Maria G. Theodoridis, Xenophon Milner, Marianne Liu, Yingshan Chourdakis, Michael Effects of Long-Versus Short-Term Exposure to the Mediterranean Diet on Skin Microvascular Function and Quality of Life of Healthy Adults in Greece and the UK |
title | Effects of Long-Versus Short-Term Exposure to the Mediterranean Diet on Skin Microvascular Function and Quality of Life of Healthy Adults in Greece and the UK |
title_full | Effects of Long-Versus Short-Term Exposure to the Mediterranean Diet on Skin Microvascular Function and Quality of Life of Healthy Adults in Greece and the UK |
title_fullStr | Effects of Long-Versus Short-Term Exposure to the Mediterranean Diet on Skin Microvascular Function and Quality of Life of Healthy Adults in Greece and the UK |
title_full_unstemmed | Effects of Long-Versus Short-Term Exposure to the Mediterranean Diet on Skin Microvascular Function and Quality of Life of Healthy Adults in Greece and the UK |
title_short | Effects of Long-Versus Short-Term Exposure to the Mediterranean Diet on Skin Microvascular Function and Quality of Life of Healthy Adults in Greece and the UK |
title_sort | effects of long-versus short-term exposure to the mediterranean diet on skin microvascular function and quality of life of healthy adults in greece and the uk |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835788/ https://www.ncbi.nlm.nih.gov/pubmed/31623223 http://dx.doi.org/10.3390/nu11102487 |
work_keys_str_mv | AT klonizakismarkos effectsoflongversusshorttermexposuretothemediterraneandietonskinmicrovascularfunctionandqualityoflifeofhealthyadultsingreeceandtheuk AT grammatikopouloumariag effectsoflongversusshorttermexposuretothemediterraneandietonskinmicrovascularfunctionandqualityoflifeofhealthyadultsingreeceandtheuk AT theodoridisxenophon effectsoflongversusshorttermexposuretothemediterraneandietonskinmicrovascularfunctionandqualityoflifeofhealthyadultsingreeceandtheuk AT milnermarianne effectsoflongversusshorttermexposuretothemediterraneandietonskinmicrovascularfunctionandqualityoflifeofhealthyadultsingreeceandtheuk AT liuyingshan effectsoflongversusshorttermexposuretothemediterraneandietonskinmicrovascularfunctionandqualityoflifeofhealthyadultsingreeceandtheuk AT chourdakismichael effectsoflongversusshorttermexposuretothemediterraneandietonskinmicrovascularfunctionandqualityoflifeofhealthyadultsingreeceandtheuk |