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EphA2-Receptor Targeted PEGylated Nanoliposomes for the Treatment of BRAF(V600E) Mutated Parent- and Vemurafenib-Resistant Melanoma

The clinical outcomes of malignant melanoma have improved with the introduction of mitogen-activated protein kinase kinase (MEK) inhibitors. However, off-target toxicities of the MEK inhibitor trametinib (TMB) often result in dose interruption and discontinuation of therapy. The purpose of this stud...

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Detalles Bibliográficos
Autores principales:	Fu, Yige, Rathod, Drishti, Abo-Ali, Ehab M., Dukhande, Vikas V., Patel, Ketan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836218/ https://www.ncbi.nlm.nih.gov/pubmed/31581483 http://dx.doi.org/10.3390/pharmaceutics11100504

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